Corticosteroids
Prednisone
Brand Names
- Solu-Medrol
- Decadron
- Deltasone
Side Effects
- High blood sugar
- High blood pressure
- High Cholesterol
- Mood changes
- Insomnia
- Water Retention
Calcineurin Inhibitors
Tacrolimus (FK 506)
Brand Names
- Prograf
Side Effects
- High blood sugar
- High blood pressure
- High Cholesterol
- Kidney toxicity
- Neuro toxicity
- Headaches
- Tremors
- High potassium
- Low magnesium
Cyclosporine
Brand Names
- Sandimmune
- Neora
- Gengraf
Side Effects
- High blood sugar
- High blood pressure
- High Cholesterol
- Kidney toxicity
- Headaches
- Tremors
- Seizures
- High Potassium
Antimetabolites
Azathioprine (AZA)
Brand Names
- Imuran
Side Effects
- Low blood counts
- Stomach Upset
- Rash
Mycophenolate; Mofetil
Brand Name
- Cellcept
Side Effects
- Diarrhea
- Nausea
- Vomiting
- Stomach Ulcers
- Low WBC
Polyclonal Abs
Antithymocyte globulin
Brand Names
- Thymoglobulin
- ATGAM
Side Effects
- Usually less severe than OKT3
Anti-CD3 monoclonal Abs
Muromonab-CD3
Brand Name
- OKT3
Side Effects
- Flu-like symptoms
- Fever
- Chills
- Headache
- Diarrhea
- Myalgia
- Pulmonary edema
- Seizures
- Increase risk of
- infections, meningitis
Anti-IL-2 receptor monoclona Abs
Daclizumab
Brand Name
- Zenapax
TOR inhibitors
Sirolimus or Rapamycin
Brand Name
- Rapamune
Side Effects
- High Cholesterol and lipids
- Low blood counts
- Diarrhea
- Mouth Ulcers