Research Summary
I am interested in the relationship between intestinal inflammation and colorectal cancer, especially the microbiome and its role in promoting or protecting against carcinogenesis. My MD study was on the mechanisms of the mTOR signaling pathway and the STAT3 signaling pathway, and their effect on intestinal inflammation-induced colorectal cancer.
I joined Dr. Christian Jobin’s lab in 2016 to study how the microbiome promotes or protects against the development of intestinal inflammation -induced colorectal cancer. My research is focused on the CDT-producing bacteria Campylobacter jejuni and the induction of colorectal cancer.
Education
- 2016-Present
University of Florida
Postdoc - 2014-Present
Sixth Affiliate Hospital of Sun Yat-sen University, China
Attending, Gastrointestinal Department - 2012-2014
Sixth Affiliate Hospital of Sun Yat-sen University, China
Resident, Gastrointestinal Department - 2004-2012
Zhongshan Medical school of Sun Yat-sen University, China
Medicine
Publications
- HES1 promotes metastasis and predicts poor survival in patients with colorectal cancer
- PAF receptor antagonist Ginkgolide B inhibits tumourigenesis and angiogenesis in colitis-associated cancer
- Role of microRNA221 in regulating normal mammary epithelial hierarchy and breast cancer stem-like cells
- Activation of the mTORC1 and STAT3 pathways promotes the malignant transformation of colitis in mice