Josee Gauthier

Josee Gauthier,

Scientific Laboratory Manager

Department: MD-GASTROENTEROLOGY
Business Phone: (352) 294-5092
Business Email: josee.gauthier@ufl.edu

Research Profile

I have 30 years of experience in conducting Biomedical Research. I was involved in research on various inflammatory diseases and sensory mechanisms, such as Rheumatoid Arthritis, Lupus Erythematous and mu-opioid receptor genes in an academic setting. I’ve worked in the corporate world for GlaxoWelcome developing a new medication (Lamivudine) for Hepatitis B and studying HBV mutation under drug pressure, and then for GlaxoSmithKline with a team looking for new applications of approved drugs on unexpected targets.

I joined Dr. Christian Jobin’s laboratory at UF in 2013. In this lab, I am in charge of a group of talented post-docs and a technician working on the influence of the microbiota on colon cancer and intestinal inflammation.

Open Researcher and Contributor ID (ORCID)

0000-0002-2251-1202

Publications

2024
Effect of Routine Gastric Residual Aspiration on the Preterm Infant Fecal Microbiome.
American journal of perinatology. 41(S 01):e212-e220 [DOI] 10.1055/a-1877-6306. [PMID] 35709728.
2023
Skin microbiome sampling in the preterm neonate.
Pediatric dermatology. 40(1):129-131 [DOI] 10.1111/pde.15158. [PMID] 36385397.
2021
Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis
Science. 374(6564):216-224 [DOI] 10.1126/science.abf8403.
2021
Increased ACE2 Levels and Mortality Risk of Patients With COVID-19 on Proton Pump Inhibitor Therapy.
The American journal of gastroenterology. 116(8):1638-1645 [DOI] 10.14309/ajg.0000000000001311. [PMID] 34047305.
2021
The gut microbiome of COVID-19 recovered patients returns to uninfected status in a minority-dominated United States cohort
Gut Microbes. 13(1) [DOI] 10.1080/19490976.2021.1926840. [PMID] 34100340.
2020
Baseline Gut Microbiota Composition Is Associated with Major Infections Early after Hematopoietic Cell Transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 26(11):2001-2010 [DOI] 10.1016/j.bbmt.2020.07.023. [PMID] 32717434.
2020
Human Colon Mucosal Biofilms and Murine Host Communicate via Altered mRNA and microRNA Expression during Cancer.
mSystems. 5(1) [DOI] 10.1128/mSystems.00451-19. [PMID] 31937674.
2019
Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic.
The Journal of clinical investigation. 129(4):1699-1712 [DOI] 10.1172/JCI124196. [PMID] 30855275.
2019
Initial microbial community of the neonatal stomach immediately after birth
Gut Microbes. 10(3):289-297 [DOI] 10.1080/19490976.2018.1520578. [PMID] 30404568.
2018
Intestinal microbiota enhances pancreatic carcinogenesis in preclinical models.
Carcinogenesis. 39(8):1068-1078 [DOI] 10.1093/carcin/bgy073. [PMID] 29846515.
2018
Microbiota-Derived Metabolic Factors Reduce Campylobacteriosis in Mice
Gastroenterology. 154(6):1751-1763.e2 [DOI] 10.1053/j.gastro.2018.01.042. [PMID] 29408609.
2017
Locoregional Effects of Microbiota in a Preclinical Model of Colon Carcinogenesis.
Cancer research. 77(10):2620-2632 [DOI] 10.1158/0008-5472.CAN-16-3472. [PMID] 28416491.
2015
COMT gene locus: new functional variants.
Pain. 156(10):2072-2083 [DOI] 10.1097/j.pain.0000000000000273. [PMID] 26207649.
2011
Structural basis for μ-opioid receptor binding and activation.
Structure (London, England : 1993). 19(11):1683-90 [DOI] 10.1016/j.str.2011.08.003. [PMID] 22078567.
2010
A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism.
Molecular pain. 6 [DOI] 10.1186/1744-8069-6-33. [PMID] 20525224.
2009
Expansion of the human mu-opioid receptor gene architecture: novel functional variants.
Human molecular genetics. 18(6):1037-51 [DOI] 10.1093/hmg/ddn439. [PMID] 19103668.

Education

Chemistry and Biology
1987 · College of Levis-Lauzon, Canada
Science
1984 · College of Abitibi-Temiscamingue, Canada

Contact Details

Phones:
Business:
(352) 294-5092
Emails:
Addresses:
Business Mailing:
CGRC-465
PO Box : 103633
2033 MOWRY RD
GAINESVILLE FL 32610
Business Street:
CGRC-465
2033 Mowry Rd
Gainesville FL 32610