Josee Gauthier

Josee Gauthier,

Scientific Laboratory Manager

Department: MD-GASTROENTEROLOGY
Business Phone: (352) 294-5092
Business Email: josee.gauthier@ufl.edu

Research Profile

I have 30 years of experience in conducting Biomedical Research. I was involved in research on various inflammatory diseases and sensory mechanisms, such as Rheumatoid Arthritis, Lupus Erythematous and mu-opioid receptor genes in an academic setting. I’ve worked in the corporate world for GlaxoWelcome developing a new medication (Lamivudine) for Hepatitis B and studying HBV mutation under drug pressure, and then for GlaxoSmithKline with a team looking for new applications of approved drugs on unexpected targets.

I joined Dr. Christian Jobin’s laboratory at UF in 2013. In this lab, I am in charge of a group of talented post-docs and a technician working on the influence of the microbiota on colon cancer and intestinal inflammation.

Publications

2020
Baseline Gut Microbiota Composition Is Associated with Major Infections Early after Hematopoietic Cell Transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 26(11):2001-2010 [DOI] 10.1016/j.bbmt.2020.07.023. [PMID] 32717434.
2020
Human Colon Mucosal Biofilms and Murine Host Communicate via Altered mRNA and microRNA Expression during Cancer.
mSystems. 5(1) [DOI] 10.1128/mSystems.00451-19. [PMID] 31937674.
2019
Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic.
The Journal of clinical investigation. 129(4):1699-1712 [DOI] 10.1172/JCI124196. [PMID] 30855275.
2019
Initial microbial community of the neonatal stomach immediately after birth.
Gut microbes. 10(3):289-297 [DOI] 10.1080/19490976.2018.1520578. [PMID] 30404568.
2018
Intestinal microbiota enhances pancreatic carcinogenesis in preclinical models.
Carcinogenesis. 39(8):1068-1078 [DOI] 10.1093/carcin/bgy073. [PMID] 29846515.
2018
Microbiota-Derived Metabolic Factors Reduce Campylobacteriosis in Mice.
Gastroenterology. 154(6):1751-1763.e2 [DOI] 10.1053/j.gastro.2018.01.042. [PMID] 29408609.
2017
Locoregional Effects of Microbiota in a Preclinical Model of Colon Carcinogenesis.
Cancer research. 77(10):2620-2632 [DOI] 10.1158/0008-5472.CAN-16-3472. [PMID] 28416491.
2015
COMT gene locus: new functional variants.
Pain. 156(10):2072-2083 [DOI] 10.1097/j.pain.0000000000000273. [PMID] 26207649.
2011
Structural basis for μ-opioid receptor binding and activation.
Structure (London, England : 1993). 19(11):1683-90 [DOI] 10.1016/j.str.2011.08.003. [PMID] 22078567.
2010
A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism.
Molecular pain. 6 [DOI] 10.1186/1744-8069-6-33. [PMID] 20525224.
2009
Expansion of the human mu-opioid receptor gene architecture: novel functional variants.
Human molecular genetics. 18(6):1037-51 [DOI] 10.1093/hmg/ddn439. [PMID] 19103668.

Education

Chemistry and Biology
1987 · College of Levis-Lauzon, Canada
Science
1984 · College of Abitibi-Temiscamingue, Canada

Contact Details

Phones:
Business:
(352) 294-5092
Emails: