Christian Jobin

Christian Jobin, Ph.D.

Professor Of Medicine; Principal Investigator

Department: MD-GASTROENTEROLOGY
Business Phone: (352) 294-5148
Business Email: cjobin@ufl.edu

Accomplishments

Associate Editor
2017-2020 · Microbiome
Chair study section for Program Project Grant exploring the metabolic, epigenetic and microbiome drivers of inflammation driven malignancy
2017 · Terry Fox Research Institute
Permanent Member
2015-2020 · NIH GMPB
UF Senior Faculty Excellence in Research Award
2015 · University of Florida
Study Section Memberships – Advisory Board
2014-2016 · CIHR Institute Advisory Board of Infection and Immunity
Study Section Memberships – Advisory Board
2014-2015 · AICR
Study Section Memberships -Advisory Board
2014-2015 · American Society for Cancer
Study Section Memberships – Advisory Board
2013-2020 · NIH NCI Chair ZRG1 DKUS-D: Role of the Microflora in the Etiology of Gastrointestinal Cancer
Study Section Memberships – Advisory Board
2011-2020 · Ad Hoc NIH Gastrointestinal Mucosal Pathobiology (GMBP)
Study Section Memberships – Advisory Board
2010-2013 · Canadian Institutes of Health Research, Vanier Canada Graduate Scholarships
Admission Committee
2009-2012 · UNC Biological and Biomedical Sciences Program
IBD: Associate Editor
2008-2016 · Cell Biology/Biochemistry/Molecular Biology
Study Section Memberships – Advisory Board
2008-2011 · CCFA Study section (Fellowship and Career Awards)
Study Section
2007-2020 · NIH Tumor Microenvironment (TME)
IBD: Section Editor
2007-2008 · Cell Biology/Biochemistry/Molecular Biology
Editorial Board Member
2005-2010 · Gastroenterology
Fireman Young Scientist Basic Research Award
2005 · American Gastroenterological Association
Junior Faculty Development Award
2005 · UNC
University Research Council Award
2004 · Mucosal Immunology Society
Study Section Memberships – Advisory Board
2003-2007 · Canadian Institutes of Health Research,  Experimental Medicine
Study Section Memberships – Advisory Board
2002-2020 · Ad Hoc NIH Special Emphasis Panel NIDDK
Editorial Board Member
2001-2009 · American Journal of Physiology
Anne Ferguson Award
1999 · Mucosal Immunology Society
Young investigator travel award
1999 · Mucosal Immunology
Career Development Award
1998-1999 · CCFA
CCFA Young IBD Investigator Award
1998 · “Regulation and modulation of the IkB/NF-kB transcriptional system in intestinal epithelial cells”
University Research Council Award
1998 · University Research Council Award
CCFA young investigator travel award
1996 · “Immune/non-immune cell interaction in intestinal inflammation” meeting in Florida
CCFA young investigator travel award
1995 · “Interactions between genetics and microbiology in inflammatory bowel disease” meeting in South Carolina
Ph.D fellowships
1991-1993 · Laval University
Ph.D fellowship
1990-1991 · Hôpital Saint-François d’Assise

Publications

2021
Avenanthramide Metabotype from Whole-Grain Oat Intake is Influenced by Faecalibacterium prausnitzii in Healthy Adults.
The Journal of nutrition. [DOI] 10.1093/jn/nxab006. [PMID] 33694368.
2021
Bacteria break barrier to promote metastasis.
Cancer cell. [DOI] 10.1016/j.ccell.2021.03.009. [PMID] 33891891.
2021
Bacterial Swarmers Enriched During Intestinal Stress Ameliorate Damage.
Gastroenterology. [DOI] 10.1053/j.gastro.2021.03.017. [PMID] 33741315.
2021
Black Tea Theaflavin Detoxifies Metabolic Toxins in the Intestinal Tract of Mice.
Molecular nutrition & food research. 65(4) [DOI] 10.1002/mnfr.202000887. [PMID] 33381889.
2021
Gut Microbiota Dysbiosis Associated with Persistent Fatigue in Hematopoietic Cell Transplantation Survivors.
Transplantation and cellular therapy. [DOI] 10.1016/j.jtct.2021.02.017. [PMID] 33775619.
2021
Implications of the microbiome in the development and treatment of pancreatic cancer: Thinking outside of the box by looking inside the gut.
Neoplasia (New York, N.Y.). 23(2):246-256 [DOI] 10.1016/j.neo.2020.12.008. [PMID] 33418277.
2021
Microbiome-Derived Liquid Biopsy: New Hope for Cancer Screening?
Clinical chemistry. 67(3):463-465 [DOI] 10.1093/clinchem/hvaa240. [PMID] 33277898.
2021
Microbiota phylogenic analysis revealed decreased abundance of Faecalibacterium prausnitzii, an anti-inflammatory commensal bacterium, in patients with chronic graft-versus-host disease.
Hematology/oncology and stem cell therapy. [DOI] 10.1016/j.hemonc.2021.03.004. [PMID] 33785388.
2021
NTPDase8 protects mice from intestinal inflammation by limiting P2Y6 receptor activation: identification of a new pathway of inflammation for the potential treatment of IBD.
Gut. [DOI] 10.1136/gutjnl-2020-320937. [PMID] 33452178.
2020
A mutational signature that can be made by a bacterium arises in human colon cancer.
Nature. 580(7802):194-195 [DOI] 10.1038/d41586-020-00818-7. [PMID] 32203380.
2020
Amending microbiota by targeting intestinal inflammation with TNF blockade attenuates development of colorectal cancer.
Nature cancer. 1(7):723-734 [DOI] 10.1038/s43018-020-0078-7. [PMID] 33768208.
2020
Baseline Gut Microbiota Composition Is Associated with Major Infections Early after Hematopoietic Cell Transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 26(11):2001-2010 [DOI] 10.1016/j.bbmt.2020.07.023. [PMID] 32717434.
2020
Characterization of the bacterial microbiome among free-ranging bottlenose dolphins (Tursiops truncatus).
Heliyon. 6(6) [DOI] 10.1016/j.heliyon.2020.e03944. [PMID] 32577542.
2020
Dietary iron variably modulates assembly of the intestinal microbiota in colitis-resistant and colitis-susceptible mice.
Gut microbes. 11(1):32-50 [DOI] 10.1080/19490976.2019.1599794. [PMID] 31179826.
2020
Far reach of Fusobacterium nucleatum in cancer metastasis.
Gut. [DOI] 10.1136/gutjnl-2020-323496. [PMID] 33323393.
2020
Gut microbiota maturation during early human life induces enterocyte proliferation via microbial metabolites.
BMC microbiology. 20(1) [DOI] 10.1186/s12866-020-01892-7. [PMID] 32652929.
2020
Human Colon Mucosal Biofilms and Murine Host Communicate via Altered mRNA and microRNA Expression during Cancer.
mSystems. 5(1) [DOI] 10.1128/mSystems.00451-19. [PMID] 31937674.
2020
Microbiota in pancreatic health and disease: the next frontier in microbiome research.
Nature reviews. Gastroenterology & hepatology. 17(1):53-64 [DOI] 10.1038/s41575-019-0242-7. [PMID] 31811279.
2020
Oral therapy with colonization factor antigen I prevents development of type 1 diabetes in Non-obese Diabetic mice.
Scientific reports. 10(1) [DOI] 10.1038/s41598-020-62881-4. [PMID] 32273533.
2020
Seaweed natural products modify the host inflammatory response via Nrf2 signaling and alter colon microbiota composition and gene expression.
Free radical biology & medicine. 146:306-323 [DOI] 10.1016/j.freeradbiomed.2019.09.013. [PMID] 31536771.
2020
The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View.
Trends in cancer. 6(3):192-204 [DOI] 10.1016/j.trecan.2020.01.004. [PMID] 32101723.
2019
Campylobacter jejuni promotes colorectal tumorigenesis through the action of cytolethal distending toxin.
Gut. 68(2):289-300 [DOI] 10.1136/gutjnl-2018-317200. [PMID] 30377189.
2019
Fecal Microbial Transplantation for Diseases Beyond Recurrent Clostridium Difficile Infection.
Gastroenterology. 157(3):624-636 [DOI] 10.1053/j.gastro.2019.04.053. [PMID] 31220424.
2019
Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic.
The Journal of clinical investigation. 129(4):1699-1712 [DOI] 10.1172/JCI124196. [PMID] 30855275.
2019
Initial microbial community of the neonatal stomach immediately after birth.
Gut microbes. 10(3):289-297 [DOI] 10.1080/19490976.2018.1520578. [PMID] 30404568.
2019
International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis.
Gut. 68(9):1624-1632 [DOI] 10.1136/gutjnl-2019-318556. [PMID] 31092590.
2019
Microbial Colonization Coordinates the Pathogenesis of a Klebsiella pneumoniae Infant Isolate.
Scientific reports. 9(1) [DOI] 10.1038/s41598-019-39887-8. [PMID] 30833613.
2019
Microbiota and cancer immunotherapy: in search of microbial signals.
Gut. 68(3):385-388 [DOI] 10.1136/gutjnl-2018-317220. [PMID] 30530851.
2019
Microbiota facilitates the formation of the aminated metabolite of green tea polyphenol (-)-epigallocatechin-3-gallate which trap deleterious reactive endogenous metabolites.
Free radical biology & medicine. 131:332-344 [DOI] 10.1016/j.freeradbiomed.2018.12.023. [PMID] 30578921.
2019
Yersiniabactin-Producing Adherent/Invasive Escherichia coli Promotes Inflammation-Associated Fibrosis in Gnotobiotic Il10-/- Mice.
Infection and immunity. 87(11) [DOI] 10.1128/IAI.00587-19. [PMID] 31481410.
2018
Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma.
Nature communications. 9(1) [DOI] 10.1038/s41467-018-04111-0. [PMID] 29700302.
2018
Colorectal cancer: Hand-in-hand – colorectal cancer metastasizes with microorganisms.
Nature reviews. Gastroenterology & hepatology. 15(3):133-134 [DOI] 10.1038/nrgastro.2017.186. [PMID] 29339812.
2018
Dual-route targeted vaccine protects efficiently against botulinum neurotoxin A complex.
Vaccine. 36(1):155-164 [DOI] 10.1016/j.vaccine.2017.11.008. [PMID] 29180028.
2018
Intestinal microbiota enhances pancreatic carcinogenesis in preclinical models.
Carcinogenesis. 39(8):1068-1078 [DOI] 10.1093/carcin/bgy073. [PMID] 29846515.
2018
Microbial dysbiosis associated with impaired intestinal Na+/H+ exchange accelerates and exacerbates colitis in ex germ free mice
Mucosal Immunology.
2018
Microbial dysbiosis associated with impaired intestinal Na+/H+ exchange accelerates and exacerbates colitis in ex-germ free mice.
Mucosal immunology. 11(5):1329-1341 [DOI] 10.1038/s41385-018-0035-2. [PMID] 29875400.
2018
Microbial networking in cancer: when two toxins collide.
British journal of cancer. 118(11):1407-1409 [DOI] 10.1038/s41416-018-0101-2. [PMID] 29773837.
2018
Microbiota-Derived Metabolic Factors Reduce Campylobacteriosis in Mice.
Gastroenterology. 154(6):1751-1763.e2 [DOI] 10.1053/j.gastro.2018.01.042. [PMID] 29408609.
2018
Precision medicine using microbiota.
Science (New York, N.Y.). 359(6371):32-34 [DOI] 10.1126/science.aar2946. [PMID] 29302001.
2018
Transcription factor Bcl11b is central for Th2 cell differentiation in asthma and immune response to helminths
Nature Communications. 9(1)
2017
Cancer treatment: Bacterial snack attack deactivates a drug.
Nature. 550(7676):337-339 [DOI] 10.1038/550337a. [PMID] 29052621.
2017
Carcinogenesis and therapeutics: the microbiota perspective.
Nature microbiology. 2 [DOI] 10.1038/nmicrobiol.2017.8. [PMID] 28225000.
2017
ClbM is a versatile, cation-promiscuous MATE transporter found in the colibactin biosynthetic gene cluster.
Biochemical and biophysical research communications. 482(4):1233-1239 [DOI] 10.1016/j.bbrc.2016.12.018. [PMID] 27939886.
2017
Human Intestinal Microbiota and Colorectal Cancer: Moving Beyond Associative Studies.
Gastroenterology. 153(6):1475-1478 [DOI] 10.1053/j.gastro.2017.10.030. [PMID] 29100848.
2017
Locoregional Effects of Microbiota in a Preclinical Model of Colon Carcinogenesis.
Cancer research. 77(10):2620-2632 [DOI] 10.1158/0008-5472.CAN-16-3472. [PMID] 28416491.
2017
Microbiota as a mediator of cancer progression and therapy.
Translational research : the journal of laboratory and clinical medicine. 179:139-154 [DOI] 10.1016/j.trsl.2016.07.021. [PMID] 27554797.
2017
Novel insights into microbiome in colitis and colorectal cancer.
Current opinion in gastroenterology. 33(6):422-427 [DOI] 10.1097/MOG.0000000000000399. [PMID] 28877044.
2017
Optimized multiplex immunofluorescence single-cell analysis reveals tuft cell heterogeneity.
JCI insight. 2(11) [DOI] 10.1172/jci.insight.93487. [PMID] 28570279.
2017
The Aryl Hydrocarbon Receptor Preferentially Marks and Promotes Gut Regulatory T Cells.
Cell reports. 21(8):2277-2290 [DOI] 10.1016/j.celrep.2017.10.114. [PMID] 29166616.
2017
Workshop Report: Modulation of Antitumor Immune Responses by Dietary and Microbial Metabolites.
Journal of the National Cancer Institute. 109(6) [DOI] 10.1093/jnci/djx040. [PMID] 30053241.
2016
A Rapid Screenable Assay for Compounds That Protect Against Intestinal Injury in Zebrafish Larva.
Methods in molecular biology (Clifton, N.J.). 1422:281-93 [DOI] 10.1007/978-1-4939-3603-8_25. [PMID] 27246041.
2016
Altered intestinal microbiota-host mitochondria crosstalk in new onset Crohn’s disease.
Nature communications. 7 [DOI] 10.1038/ncomms13419. [PMID] 27876802.
2016
Gut Microbiota and a Selectively Bred Taste Phenotype: A Novel Model of Microbiome-Behavior Relationships.
Psychosomatic medicine. 78(5):610-9 [DOI] 10.1097/PSY.0000000000000318. [PMID] 27035357.
2016
High purity galacto-oligosaccharides enhance specific Bifidobacterium species and their metabolic activity in the mouse gut microbiome.
Beneficial microbes. 7(2):247-64 [DOI] 10.3920/BM2015.0114. [PMID] 26839072.
2016
Intestinal Microbiota in Inflammatory Bowel Disease and Carcinogenesis: Implication for Therapeutics
Clinical Pharmacology & Therapeutics. 99(6):585-587 [DOI] 10.1002/cpt.348. [PMID] 26850686.
2016
Intestinal Microbiota in Inflammatory Bowel Disease and Carcinogenesis: Implication for Therapeutics.
Clinical pharmacology and therapeutics. 99(6):585-7 [DOI] 10.1002/cpt.348. [PMID] 26850686.
2016
MATE transport of the E. coli-derived genotoxin colibactin.
Nature microbiology. 1 [DOI] 10.1038/nmicrobiol.2015.9. [PMID] 27571755.
2016
Microbiota and host immune responses: a love-hate relationship.
Immunology. 147(1):1-10 [DOI] 10.1111/imm.12538. [PMID] 26439191.
2016
Murine Model of Intestinal Ischemia-reperfusion Injury.
Journal of visualized experiments : JoVE. (111) [DOI] 10.3791/53881. [PMID] 27213580.
2016
The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals.
Cell reports. 14(11):2562-75 [DOI] 10.1016/j.celrep.2016.02.064. [PMID] 26971998.
2015
Differential Relevance of NF-κB and JNK in the Pathophysiology of Hemorrhage/Resususcitation-Induced Liver Injury after Chronic Ethanol Feeding.
PloS one. 10(9) [DOI] 10.1371/journal.pone.0137875. [PMID] 26367181.
2015
Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt.
Nature medicine. 21(8):906-13 [DOI] 10.1038/nm.3908. [PMID] 26107252.
2015
Microbial activities and intestinal homeostasis: A delicate balance between health and disease.
Cellular and molecular gastroenterology and hepatology. 1(1):28-40 [PMID] 25729763.
View on: PubMed
2015
Partial depletion of the proinflammatory monocyte population is neuroprotective in the myenteric plexus but not in the basal ganglia in a MPTP mouse model of Parkinson’s disease.
Brain, behavior, and immunity. 46:154-67 [DOI] 10.1016/j.bbi.2015.01.009. [PMID] 25637482.
2015
Professor Arlette Darfeuille-Michaud: the discovery of adherent-invasive Escherichia coli.
Journal of Crohn's & colitis. 9(5):373-5 [DOI] 10.1093/ecco-jcc/jjv044. [PMID] 25759068.
2015
SCFAs Take a Toll En Route to Metabolic Syndrome.
Cell metabolism. 22(6):954-6 [DOI] 10.1016/j.cmet.2015.11.006. [PMID] 26636491.
2015
The Microbiome and Cancer: Is the ‘Oncobiome’ Mirage Real?
Trends in cancer. 1(1):24-35 [PMID] 26568984.
View on: PubMed
2015
The Role of Curcumin in Modulating Colonic Microbiota During Colitis and Colon Cancer Prevention.
Inflammatory bowel diseases. 21(11):2483-94 [DOI] 10.1097/MIB.0000000000000522. [PMID] 26218141.
2014
Bugs and food: a recipe for cancer?
Cell metabolism. 20(6):937-8 [DOI] 10.1016/j.cmet.2014.11.010. [PMID] 25470545.
2014
Chemotherapy, immunity and microbiota–a new triumvirate?
Nature medicine. 20(2):126-7 [DOI] 10.1038/nm.3473. [PMID] 24504404.
2014
Chronic Ethanol Feeding Modulates Inflammatory Mediators, Activation Of Nuclear Factor-Κb, And Responsiveness To Endotoxin In Murine Kupffer Cells And Circulating Leukocytes.
Mediators of Inflammation. 2014 [DOI] 10.1155/2014/808695. [PMID] 24623963.
2014
Commensal microbiota stimulate systemic neutrophil migration through induction of serum amyloid A.
Cellular microbiology. 16(7):1053-67 [DOI] 10.1111/cmi.12257. [PMID] 24373309.
2014
Could a swimming creature inform us on intestinal diseases? Lessons from zebrafish.
Inflammatory bowel diseases. 20(5):956-66 [DOI] 10.1097/01.MIB.0000442923.85569.68. [PMID] 24577115.
2014
Do bugs define cancer geography?
The Journal of experimental medicine. 211(3) [DOI] 10.1084/jem.2113insight3. [PMID] 24616475.
2014
From promotion to management: the wide impact of bacteria on cancer and its treatment.
BioEssays : news and reviews in molecular, cellular and developmental biology. 36(7):658-64 [DOI] 10.1002/bies.201400015. [PMID] 24752750.
2014
Fusobacterium and Enterobacteriaceae: important players for CRC?
Immunology letters. 162(2 Pt A):54-61 [DOI] 10.1016/j.imlet.2014.05.014. [PMID] 24972311.
2014
Glass Microparticulate Ingestion: An Unusual And Difficult-To-Diagnose Cause Of Chronic Abdominal Pain.
Acg Case Reports Journal. 1(3):137-9 [DOI] 10.14309/crj.2014.29. [PMID] 26157853.
2014
GPR109a: the missing link between microbiome and good health?
Immunity. 40(1):8-10 [DOI] 10.1016/j.immuni.2013.12.009. [PMID] 24439263.
2014
Gut commensal bacteria and regional Wnt gene expression in the proximal versus distal colon.
The American journal of pathology. 184(3):592-9 [DOI] 10.1016/j.ajpath.2013.11.029. [PMID] 24418259.
2014
Lactobacillus Acidophilus Ncfm Affects Colonic Mucosal Opioid Receptor Expression In Patients With Functional Abdominal Pain – A Randomised Clinical Study.
Alimentary Pharmacology & Therapeutics. 40(2):200-7 [DOI] 10.1111/apt.12800. [PMID] 24853043.
2014
Microbial genomic analysis reveals the essential role of inflammation in bacteria-induced colorectal cancer.
Nature communications. 5 [DOI] 10.1038/ncomms5724. [PMID] 25182170.
2014
Microbial imbalance and intestinal pathologies: connections and contributions.
Disease models & mechanisms. 7(10):1131-42 [DOI] 10.1242/dmm.016428. [PMID] 25256712.
2014
Microbial-derived butyrate: an oncometabolite or tumor-suppressive metabolite?
Cell host & microbe. 16(2):143-145 [DOI] 10.1016/j.chom.2014.07.011. [PMID] 25121740.
2014
Nucleotide-binding oligomerization domain-containing protein 2 controls host response to Campylobacter jejuni in Il10-/- mice.
The Journal of infectious diseases. 210(7):1145-54 [DOI] 10.1093/infdis/jiu148. [PMID] 24620022.
2014
Protective mucosal immunity mediated by epithelial CD1d and IL-10.
Nature. 509(7501):497-502 [DOI] 10.1038/nature13150. [PMID] 24717441.
2014
The microbiota protects against ischemia/reperfusion-induced intestinal injury through nucleotide-binding oligomerization domain-containing protein 2 (NOD2) signaling.
The American journal of pathology. 184(11):2965-75 [DOI] 10.1016/j.ajpath.2014.07.014. [PMID] 25204845.
2014
Time To Enlist Life-Saving, Gutsy Allies
New Scientist. 224(2992):28-29
2013
[Microbial dysbiosis, a new risk factor in colorectal cancer?].
Medecine sciences : M/S. 29(6-7):582-5 [DOI] 10.1051/medsci/2013296010. [PMID] 23859512.
2013
Activation Of Nf-Κb After Chronic Ethanol Intake And Haemorrhagic Shock/Resuscitation In Mice.
British journal of pharmacology. 170(3):506-18 [DOI] 10.1111/bph.12224. [PMID] 23646923.
2013
Challenges in IBD research: update on progress and prioritization of the CCFA’s research agenda.
Inflammatory bowel diseases. 19(4):677-82 [DOI] 10.1097/MIB.0b013e31828134b3. [PMID] 23448796.
2013
Colorectal cancer: looking for answers in the microbiota.
Cancer discovery. 3(4):384-7 [DOI] 10.1158/2159-8290.CD-13-0042. [PMID] 23580283.
2013
Diet, microbiome, and the intestinal epithelium: an essential triumvirate?
BioMed research international. 2013 [DOI] 10.1155/2013/425146. [PMID] 23586037.
2013
Epithelial cell-specific MyD88 signaling mediates ischemia/reperfusion-induced intestinal injury independent of microbial status.
Inflammatory bowel diseases. 19(13):2857-66 [DOI] 10.1097/01.MIB.0000435445.96933.37. [PMID] 24141713.
2013
Glafenine-induced intestinal injury in zebrafish is ameliorated by μ-opioid signaling via enhancement of Atf6-dependent cellular stress responses.
Disease models & mechanisms. 6(1):146-59 [DOI] 10.1242/dmm.009852. [PMID] 22917923.
2013
Intestinal epithelial cell-derived μ-opioid signaling protects against ischemia reperfusion injury through PI3K signaling.
The American journal of pathology. 182(3):776-85 [DOI] 10.1016/j.ajpath.2012.11.021. [PMID] 23291213.
2013
Microbial Influence On Colorectal Cancer
Digestive Diseases and Sciences. 58
2013
Neonatal Fc receptor expression in dendritic cells mediates protective immunity against colorectal cancer.
Immunity. 39(6):1095-107 [DOI] 10.1016/j.immuni.2013.11.003. [PMID] 24290911.
2013
Oxymatrine prevents NF-κB nuclear translocation and ameliorates acute intestinal inflammation.
Scientific reports. 3 [DOI] 10.1038/srep01629. [PMID] 23568217.
2013
Phosphatidylinositol 3-kinase-γ signaling promotes Campylobacter jejuni-induced colitis through neutrophil recruitment in mice.
Journal of immunology (Baltimore, Md. : 1950). 190(1):357-65 [DOI] 10.4049/jimmunol.1201825. [PMID] 23180818.
2013
Stochastic changes over time and not founder effects drive cage effects in microbial community assembly in a mouse model.
The ISME journal. 7(11):2116-25 [DOI] 10.1038/ismej.2013.106. [PMID] 23823492.
2013
The complex interplay between inflammation, the microbiota and colorectal cancer.
Gut microbes. 4(3):253-8 [DOI] 10.4161/gmic.24220. [PMID] 23549517.
2013
The microbiome and cancer.
Nature reviews. Cancer. 13(11):800-12 [DOI] 10.1038/nrc3610. [PMID] 24132111.
2013
VSL#3 probiotic modifies mucosal microbial composition but does not reduce colitis-associated colorectal cancer.
Scientific reports. 3 [DOI] 10.1038/srep02868. [PMID] 24100376.
2012
A cell permeable peptide inhibitor of NFAT inhibits macrophage cytokine expression and ameliorates experimental colitis.
PloS one. 7(3) [DOI] 10.1371/journal.pone.0034172. [PMID] 22479554.
2012
Campylobacter jejuni induces colitis through activation of mammalian target of rapamycin signaling.
Gastroenterology. 142(1):86-95.e5 [DOI] 10.1053/j.gastro.2011.09.042. [PMID] 21963787.
2012
Colorectal cancer: CRC–all about microbial products and barrier function?
Nature reviews. Gastroenterology & hepatology. 9(12):694-6 [DOI] 10.1038/nrgastro.2012.220. [PMID] 23165234.
2012
Intestinal inflammation targets cancer-inducing activity of the microbiota.
Science (New York, N.Y.). 338(6103):120-3 [DOI] 10.1126/science.1224820. [PMID] 22903521.
2012
Mouse background strain profoundly influences Paneth cell function and intestinal microbial composition.
PloS one. 7(2) [DOI] 10.1371/journal.pone.0032403. [PMID] 22384242.
2012
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling.
Immunity. 36(5):742-54 [DOI] 10.1016/j.immuni.2012.03.012. [PMID] 22503542.
2012
Probiotic bacteria produce conjugated linoleic acid locally in the gut that targets macrophage PPAR γ to suppress colitis.
PloS one. 7(2) [DOI] 10.1371/journal.pone.0031238. [PMID] 22363592.
2012
Retinal not systemic oxidative and inflammatory stress correlated with VEGF expression in rodent models of insulin resistance and diabetes.
Investigative ophthalmology & visual science. 53(13):8424-32 [DOI] 10.1167/iovs.12-10207. [PMID] 23197686.
2012
The microbiota is essential for the generation of black tea theaflavins-derived metabolites.
PloS one. 7(12) [DOI] 10.1371/journal.pone.0051001. [PMID] 23227227.
2012
The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction.
Immunity. 37(5):930-46 [DOI] 10.1016/j.immuni.2012.07.016. [PMID] 23123061.
2012
Think small: zebrafish as a model system of human pathology.
Journal of biomedicine & biotechnology. 2012 [DOI] 10.1155/2012/817341. [PMID] 22701308.
2012
Time dependency and topography of hepatic nuclear factor κB activation after hemorrhagic shock and resuscitation in mice.
Shock (Augusta, Ga.). 38(5):486-92 [DOI] 10.1097/SHK.0b013e3182699072. [PMID] 22814290.
2011
Gut microbial diversity is reduced by the probiotic VSL#3 and correlates with decreased TNBS-induced colitis.
Inflammatory bowel diseases. 17(1):289-97 [DOI] 10.1002/ibd.21366. [PMID] 20564535.
2011
Gut microbiota and probiotics in colon tumorigenesis.
Cancer letters. 309(2):119-27 [DOI] 10.1016/j.canlet.2011.06.004. [PMID] 21741763.
2011
Microbial colonization induces dynamic temporal and spatial patterns of NF-κB activation in the zebrafish digestive tract.
Gastroenterology. 141(1):197-207 [DOI] 10.1053/j.gastro.2011.03.042. [PMID] 21439961.
2011
Microbiota in chronic mucosal inflammation.
International journal of inflammation. 2010 [DOI] 10.4061/2010/395032. [PMID] 21318187.
2011
Mu opioid signaling protects against acute murine intestinal injury in a manner involving Stat3 signaling.
The American journal of pathology. 179(2):673-83 [DOI] 10.1016/j.ajpath.2011.04.032. [PMID] 21801866.
2011
PI3K-dependent GSK3ß(Ser9)-phosphorylation is implicated in the intestinal epithelial cell wound-healing response.
PloS one. 6(10) [DOI] 10.1371/journal.pone.0026340. [PMID] 22039465.
2011
Pretreatment with the probiotic VSL#3 delays transition from inflammation to dysplasia in a rat model of colitis-associated cancer.
American journal of physiology. Gastrointestinal and liver physiology. 301(6):G1004-13 [DOI] 10.1152/ajpgi.00167.2011. [PMID] 21903764.
2011
Structural identification of mouse fecal metabolites of theaflavin 3,3′-digallate using liquid chromatography tandem mass spectrometry.
Journal of chromatography. A. 1218(41):7297-306 [DOI] 10.1016/j.chroma.2011.08.056. [PMID] 21906744.
2011
The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells.
Shock (Augusta, Ga.). 36(3):295-302 [DOI] 10.1097/SHK.0b013e318225ad7e. [PMID] 21844787.
2011
The struggle within: microbial influences on colorectal cancer.
Inflammatory bowel diseases. 17(1):396-409 [DOI] 10.1002/ibd.21354. [PMID] 20848537.
2010
Alleviating cancer drug toxicity by inhibiting a bacterial enzyme.
Science (New York, N.Y.). 330(6005):831-5 [DOI] 10.1126/science.1191175. [PMID] 21051639.
2010
Downregulation of aging-related Klotho gene in experimental colitis: the role of TNF and IFNGamma
Gastroenterology. 138(4):1384-1394
2010
High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse.
PloS one. 5(8) [DOI] 10.1371/journal.pone.0012191. [PMID] 20808947.
2010
MyD88 signaling in the intestine: Dr Jekyll and Mr Hyde?
Gastroenterology. 139(2):383-5 [DOI] 10.1053/j.gastro.2010.06.027. [PMID] 20600062.
2010
Probiotics and ileitis: could augmentation of TNF/NFκB activity be the answer?
Gut microbes. 1(3):196-9 [DOI] 10.4161/gmic.1.3.12485. [PMID] 21327025.
2010
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer.
The Journal of experimental medicine. 207(5):1045-56 [DOI] 10.1084/jem.20100050. [PMID] 20385749.
2010
Tumor necrosis factor and interferon-gamma down-regulate Klotho in mice with colitis.
Gastroenterology. 138(4):1384-94, 1394.e1 [DOI] 10.1053/j.gastro.2009.12.002. [PMID] 20004202.
2009
Gnotobiotic IL-10; NF-kappaB mice develop rapid and severe colitis following Campylobacter jejuni infection.
PloS one. 4(10) [DOI] 10.1371/journal.pone.0007413. [PMID] 19841748.
2009
Intestinal epithelial-derived TAK1 signaling is essential for cytoprotection against chemical-induced colitis.
PloS one. 4(2) [DOI] 10.1371/journal.pone.0004561. [PMID] 19234607.
2009
Microbes and colorectal cancer: is there a relationship?
Current oncology (Toronto, Ont.). 16(4):22-4 [PMID] 19672421.
View on: PubMed
2009
Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility.
PloS one. 4(6) [DOI] 10.1371/journal.pone.0006026. [PMID] 19551144.
2009
Tomato lycopene extract prevents lipopolysaccharide-induced NF-kappaB signaling but worsens dextran sulfate sodium-induced colitis in NF-kappaBEGFP mice.
PloS one. 4(2) [DOI] 10.1371/journal.pone.0004562. [PMID] 19234608.
2009
Wound healing responses at the gastrointestinal epithelium: a close look at novel regulatory factors and investigative approaches.
Zeitschrift fur Gastroenterologie. 47(12):1221-9 [DOI] 10.1055/s-0028-1109766. [PMID] 19960401.
2008
Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis.
Journal of immunology (Baltimore, Md. : 1950). 181(2):1143-52 [PMID] 18606667.
View on: PubMed
2008
Impaired Bcl3 up-regulation leads to enhanced lipopolysaccharide-induced interleukin (IL)-23P19 gene expression in IL-10(-/-) mice.
The Journal of biological chemistry. 283(21):14182-9 [DOI] 10.1074/jbc.M709029200. [PMID] 18375954.
2008
Interleukin-8 expression is regulated by histone deacetylases through the nuclear factor-kappaB pathway in breast cancer.
Molecular pharmacology. 74(5):1359-66 [DOI] 10.1124/mol.108.047332. [PMID] 18669446.
2008
Limited Effects Of Dietary Curcumin On Th-1 Driven Colitis In Il-10 Deficient Mice Suggest An Il-10-Dependent Mechanism Of Protection.
American Journal of Physiology-Gastrointestinal and Liver Physiology. 295(5):G1079-91 [DOI] 10.1152/ajpgi.90365.2008. [PMID] 18818316.
2008
Nf-kappa B signaling cascade and IBD: turn it down?
Inflammatory bowel diseases. 14 Suppl 2:S108-9 [DOI] 10.1002/ibd.20717. [PMID] 18816651.
2008
NF-kappaB and the intestine: friend or foe?
Inflammatory bowel diseases. 14(1):114-24 [PMID] 17763472.
View on: PubMed
2008
Regulation and functional impact of lipopolysaccharide induced Nod2 gene expression in the murine epididymal epithelial cell line PC1.
Immunology. 124(2):256-64 [DOI] 10.1111/j.1365-2567.2007.02763.x. [PMID] 18284470.
2008
Toll-like receptor 9-dependent macrophage activation by Entamoeba histolytica DNA.
Infection and immunity. 76(1):289-97 [PMID] 17984204.
View on: PubMed
2007
Amelioration of chronic murine colitis by peptide-mediated transduction of the IkappaB kinase inhibitor NEMO binding domain peptide.
Journal of immunology (Baltimore, Md. : 1950). 179(11):7852-9 [PMID] 18025231.
View on: PubMed
2007
Dual-association of gnotobiotic IL-10-/- mice with 2 nonpathogenic commensal bacteria induces aggressive pancolitis.
Inflammatory bowel diseases. 13(12):1457-66 [PMID] 17763473.
View on: PubMed
2007
Gnotobiotic IL-10-/-;NF-kappa B(EGFP) mice reveal the critical role of TLR/NF-kappa B signaling in commensal bacteria-induced colitis.
Journal of immunology (Baltimore, Md. : 1950). 178(10):6522-32 [PMID] 17475882.
View on: PubMed
2007
The flavonoid luteolin worsens chemical-induced colitis in NF-kappaB(EGFP) transgenic mice through blockade of NF-kappaB-dependent protective molecules.
PloS one. 2(7) [PMID] 17611628.
View on: PubMed
2006
Critical role for H3 phosphorylation and p38-MAPK pathway in intestinal wound-healing response
American Journal of Physiology-Cell Physiology. 207(3):809-815
2006
Wound-induced p38MAPK-dependent histone H3 phosphorylation correlates with increased COX-2 expression in enterocytes.
Journal of cellular physiology. 207(3):809-15 [PMID] 16508963.
View on: PubMed
2005
Activation of NF-kappaB following detachment delays apoptosis in intestinal epithelial cells.
Oncogene. 24(43):6482-91 [PMID] 16007176.
View on: PubMed
2005
Adenosine is a negative regulator of NF-kappaB and MAPK signaling in human intestinal epithelial cells.
Cellular immunology. 237(2):86-95 [PMID] 16413516.
View on: PubMed
2005
Inhibition of macrophage nuclear factor-kappaB leads to a dominant anti-inflammatory phenotype that attenuates glomerular inflammation in vivo.
The American journal of pathology. 167(1):27-37 [PMID] 15972949.
View on: PubMed
2005
Regulation of TNF-related apoptosis-inducing ligand-mediated death-signal pathway in human beta cells by Fas-associated death domain and nuclear factor kappaB.
Human immunology. 66(7):799-809 [PMID] 16112027.
View on: PubMed
2005
Salvia miltiorrhiza water-soluble extract, but not its constituent salvianolic acid B, abrogates LPS-induced NF-kappaB signalling in intestinal epithelial cells.
Clinical and experimental immunology. 141(2):288-97 [PMID] 15996193.
View on: PubMed
2005
Serum amyloid A activates NF-kappaB and proinflammatory gene expression in human and murine intestinal epithelial cells.
European journal of immunology. 35(3):718-26 [PMID] 15724247.
View on: PubMed
2005
STAT3 regulates NF-kappaB recruitment to the IL-12p40 promoter in dendritic cells.
Blood. 105(2):689-96 [PMID] 15251981.
View on: PubMed
2005
The flavonoid luteolin prevents lipopolysaccharide-induced NF-kappaB signalling and gene expression by blocking IkappaB kinase activity in intestinal epithelial cells and bone-marrow derived dendritic cells.
Immunology. 115(3):375-87 [PMID] 15946255.
View on: PubMed
2005
Tumor necrosis factor (TNF) alpha increases collagen accumulation and proliferation in intestinal myofibroblasts via TNF receptor 2.
The Journal of biological chemistry. 280(43):36099-109 [PMID] 16141211.
View on: PubMed
2005
Ubiquitin protein modification and signal transduction: implications for inflammatory bowel diseases.
Inflammatory bowel diseases. 11(12):1097-107 [PMID] 16306773.
View on: PubMed
2004
Differential effect of immune cells on non-pathogenic Gram-negative bacteria-induced nuclear factor-kappaB activation and pro-inflammatory gene expression in intestinal epithelial cells.
Immunology. 112(2):310-20 [PMID] 15147574.
View on: PubMed
2004
Differential Effects Of Deoxycholic Acid And Taurodeoxycholic Acid On Nf-Kappa B Signal Transduction And Il-8 Gene Expression In Colonic Epithelial Cells.
American Journal of Physiology-Gastrointestinal and Liver Physiology. 286(6):G1000-8 [PMID] 14726307.
View on: PubMed
2004
Down-regulation of MEK/ERK signaling by E-cadherin-dependent PI3K/Akt pathway in differentiating intestinal epithelial cells.
Journal of cellular physiology. 199(1):32-9 [PMID] 14978732.
View on: PubMed
2004
In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-kappa B activation using a novel gene-targeted enhanced GFP reporter gene mouse.
Journal of immunology (Baltimore, Md. : 1950). 173(3):1561-70 [PMID] 15265883.
View on: PubMed
2004
Interaction between resident luminal bacteria and the host: can a healthy relationship turn sour?
Journal of pediatric gastroenterology and nutrition. 38(2):123-36 [PMID] 14734871.
View on: PubMed
2004
Loss Of E-Cadherin Leads To Upregulation Of Nfkappab Activity In Malignant Melanoma.
Oncogene. 23(52):8509-19 [PMID] 15378016.
View on: PubMed
2004
Nf-Kappab Inducing Kinase Activates Nf-Kappab Transcriptional Activity Independently Of Ikappab Kinase Gamma Through A P38 Mapk-Dependent Rela Phosphorylation Pathway.
Cellular Signalling. 16(9):1023-32 [PMID] 15212763.
View on: PubMed
2004
NF-kappaB-inducing kinase restores defective IkappaB kinase activity and NF-kappaB signaling in intestinal epithelial cells.
Cellular signalling. 16(6):741-50 [PMID] 15093615.
View on: PubMed
2004
Role of NF-kappaB in inflammatory disorders: just when you thought you knew everything!
Journal of pediatric gastroenterology and nutrition. 38(1):109-10 [PMID] 14733184.
View on: PubMed
2003
Butyrate Modulates Intestinal Epithelial Cell-Mediated Neutrophil Migration.
Clinical and Experimental Immunology. 131(1):53-60 [DOI] 10.1046/j.1365-2249.2003.02056.x. [PMID] 12519386.
2003
Intestinal epithelial cells and innate immunity in the intestine: is CARD15/Nod2 another player?
Gastroenterology. 124(4):1145-9 [PMID] 12671908.
View on: PubMed
2003
Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells.
Hepatology (Baltimore, Md.). 37(5):1043-55 [PMID] 12717385.
View on: PubMed
2003
Transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation.
The Journal of biological chemistry. 278(26):23851-60 [PMID] 12672795.
View on: PubMed
2002
Constitutive nuclear factor-kappa B activity is required for central neuron survival.
The Journal of neuroscience : the official journal of the Society for Neuroscience. 22(19):8466-75 [PMID] 12351721.
View on: PubMed
2002
Differential requirement for NF-kappaB-inducing kinase in the induction of NF-kappaB by IL-1beta, TNF-alpha, and Fas.
American journal of physiology. Cell physiology. 283(1):C347-57 [PMID] 12055104.
View on: PubMed
2002
IKK beta and phosphatidylinositol 3-kinase/Akt participate in non-pathogenic Gram-negative enteric bacteria-induced RelA phosphorylation and NF-kappa B activation in both primary and intestinal epithelial cell lines.
The Journal of biological chemistry. 277(41):38168-78 [PMID] 12140289.
View on: PubMed
2001
Cryptosporidium Parvum Activates Nuclear Factor Kappab In Biliary Epithelia Preventing Epithelial Cell Apoptosis.
Gastroenterology. 120(7):1774-83 [PMID] 11375958.
View on: PubMed
2001
Inhibition Of Cytokine-Induced Nf-Kappab Activation By Adenovirus-Mediated Expression Of A Nf-Kappab Super-Repressor Prevents Beta-Cell Apoptosis.
Diabetes. 50(10):2219-24 [PMID] 11574401.
View on: PubMed
2001
Regulatory Role Of Phosphatidylinositol 3-Kinase On Tnf-Alpha-Induced Cyclooxygenase 2 Expression In Colonic Epithelial Cells.
Gastroenterology. 120(5):1117-27 [PMID] 11266376.
View on: PubMed
2000
Cellular Differentiation Causes A Selective Down-Regulation Of Interleukin (Il)-1Beta-Mediated Nf-Kappab Activation And Il-8 Gene Expression In Intestinal Epithelial Cells.
Journal of Biological Chemistry. 275(16):12207-13 [PMID] 10766857.
View on: PubMed
2000
Nf-Kappab Signaling Proteins As Therapeutic Targets For Inflammatory Bowel Diseases.
Inflammatory Bowel Diseases. 6(3):206-13 [PMID] 10961593.
View on: PubMed
2000
The I Kappa B/Nf-Kappa B System: A Key Determinant Of Mucosalinflammation And Protection.
American journal of physiology. Cell physiology. 278(3):C451-62 [PMID] 10712233.
View on: PubMed
1999
Curcumin blocks cytokine-mediated NF-kappa B activation and proinflammatory gene expression by inhibiting inhibitory factor I-kappa B kinase activity.
Journal of immunology (Baltimore, Md. : 1950). 163(6):3474-83 [PMID] 10477620.
View on: PubMed
1999
Molecular And Cellular Biology Of The Small Intestine.
Current Opinion in Gastroenterology. 15(2):103-7 [PMID] 17023928.
View on: PubMed
1999
Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor.
Investigative ophthalmology & visual science. 40(2):477-86 [PMID] 9950608.
View on: PubMed
1999
TNF receptor-associated factor-2 is involved in both IL-1 beta and TNF-alpha signaling cascades leading to NF-kappa B activation and IL-8 expression in human intestinal epithelial cells.
Journal of immunology (Baltimore, Md. : 1950). 162(8):4447-54 [PMID] 10201981.
View on: PubMed
1998
Cytokines Induce Nf-Kappab In Activated But Not In Quiescent Rat Hepatic Stellate Cells.
American Journal of Physiology. 275(2 Pt 1):G269-78 [DOI] 10.1152/ajpgi.1998.275.2.G269. [PMID] 9688654.
1998
Differential Expression Of Interleukin 1 Receptor Antagonist Isoforms In Human Intestinal Epithelial Cells.
Gastroenterology. 115(6):1426-38 [PMID] 9834270.
View on: PubMed
1998
Inhibition of NFkappaB in activated rat hepatic stellate cells by proteasome inhibitors and an IkappaB super-repressor.
Hepatology (Baltimore, Md.). 27(5):1285-95 [PMID] 9581682.
View on: PubMed
1998
Inhibition Of Proinflammatory Molecule Production By Adenovirus-Mediated Expression Of A Nuclear Factor Kappab Super-Repressor In Human Intestinal Epithelial Cells.
Journal of immunology (Baltimore, Md. : 1950). 160(1):410-8 [PMID] 9551998.
View on: PubMed
1998
Mediation By Nf-Kappa B Of Cytokine Induced Expression Of Intercellular Adhesion Molecule 1 (Icam-1) In An Intestinal Epithelial Cell Line, A Process Blocked By Proteasome Inhibitors.
Gut. 42(6):779-87 [DOI] 10.1136/gut.42.6.779. [PMID] 9691914.
1998
Specific Nf-Kappab Blockade Selectively Inhibits Tumour Necrosis Factor-Alpha-Induced Cox-2 But Not Constitutive Cox-1 Gene Expression In Ht-29 Cells.
Immunology. 95(4):537-43 [DOI] 10.1046/j.1365-2567.1998.00646.x. [PMID] 9893042.
1997
Differential Effects Of Cell Density On 5-Lipoxygenase (5-Lo), Five-Lipoxygenase-Activating Protein (Flap) And Interleukin-1 Beta (Il-1 Beta) Expression In Human Neutrophils.
Inflammation. 21(2):235-50 [PMID] 9187965.
View on: PubMed
1997
Evidence for altered regulation of I kappa B alpha degradation in human colonic epithelial cells.
Journal of immunology (Baltimore, Md. : 1950). 158(1):226-34 [PMID] 8977194.
View on: PubMed
1991
Differential Synthesis Of 5-Lipoxygenase In Peripheral Blood And Synovial Fluid Neutrophils In Rheumatoid Arthritis.
Journal of immunology (Baltimore, Md. : 1950). 146(8):2701-7 [PMID] 2016523.
View on: PubMed

Grants

Mar 2019 ACTIVE
Role of the microbiota in DNA methylation and CRC development
Role: Principal Investigator
Funding: CORIELL INSTITUTE FOR MEDICAL RESEARCH via NATL INST OF HLTH NCI
Jan 2019 ACTIVE
Human milk metabolomics and microbe-host interactions associated with pediatric obesity
Role: Other
Funding: NATL INST OF HLTH NIDDK
Jul 2018 ACTIVE
Role of Bacteria in Colitis-Associated Colon Cancer
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Jan 2018 ACTIVE
The role of the microbiome on pancreatic carcinogenesis in a murine model
Role: Other
Funding: AMER CANCER SOC
Dec 2017 – Feb 2019
Role of the microbiota in DNA methylation and CRC development
Role: Principal Investigator
Funding: TEMPLE UNIVERSITY via NATL INST OF HLTH NCI
Dec 2017 ACTIVE
Chemical approaches toward the identification, functional analysis, and biosynthesis of small molecule cyclomodulin
Role: Principal Investigator
Funding: YALE UNIV via NATL INST OF HLTH NCI
Oct 2016 – Sep 2018
Role of Gram negative bacterial lipopolysaccharide in CXCR4-mediated pancreatic carcinogenesis
Role: Faculty
Funding: ASSOC OF VA SURGEONS FOU
Aug 2016 ACTIVE
ACE2, Brain, Gut Dysbiosis in Pulmonary Hypertension
Role: Co-Investigator
Funding: NATL INST OF HLTH NHLBI
Jul 2016 – Jun 2019
Impact of host signaling on microbial activities in the development of colitis-associated colorectal cancer
Role: Other
Funding: CROHNS & COLITIS FOU OF AMERICA
Apr 2016 ACTIVE
Brain-Gut Microbiome-Immune Axis in Hypertension
Role: Project Manager
Funding: NATL INST OF HLTH NHLBI
Dec 2015 – Nov 2019
Mechanism by which H2S-producing bacteria influence development of colorectal cancer
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Jul 2015 ACTIVE
Florida Academic Cancer Center Alliance Seed Grants
Role: Project Manager
Funding: UF HEALTH SHANDS HOSPITAL
Jun 2015 – Nov 2017
Microbial Factors Implicated in the Development of Colorectal Cancer
Role: Principal Investigator
Funding: UF DSR OPPORTUNITY FUND
Feb 2015 ACTIVE
UF Health Cancer Center Pilot Project Grants funded through the Florida Consortium of National Cancer Institute Centers Program
Role: Project Manager
Funding: UF HEALTH SHANDS HOSPITAL
Jan 2015 ACTIVE
Impact of microbiota-mediated biotransformation of black tea polyphenols on GI health
Role: Principal Investigator
Funding: NATL CTR FOR COMPLEM AND INTEGRATIVE HLT
May 2014 – May 2019
Multiple Sponsors
Role: Principal Investigator
Funding: MULTIPLE SPONSORS
Jul 2013 ACTIVE
Florida Center for Brain Tumor Research – Statewide Brain Tumor Registry Program at the McKnight Brain Institute
Role: Project Manager
Funding: FL DEPT OF HLTH
Jul 2013 – Mar 2018
Role of Bacteria in Colitis-Associated Colon Cancer
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Jul 2013 – Jun 2016
Regulation of Immunosuppressive Molecules in IBD
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK

Teaching Profile

Courses Taught
2018-2021
GMS6065 Fundamentals of Cancer Biology
2016-2019
GMS6001 Fundamentals of Biomedical Sciences I
2018
GMS7979 Advanced Research
2018
GMS7980 Research for Doctoral Dissertation
2013
VME6934 Topics in Veterinary Medical Sciences

Contact Details

Phones:
Business:
(352) 294-5148
Emails:
Business:
cjobin@ufl.edu