Christian Jobin, Ph.D.
Professor Of Medicine; Principal Investigator
Accomplishments
Associate Editor
2017-2020
·
Microbiome
Chair study section for Program Project Grant exploring the metabolic, epigenetic and microbiome drivers of inflammation driven malignancy
2017
·
Terry Fox Research Institute
Permanent Member
2015-2020
·
NIH GMPB
UF Senior Faculty Excellence in Research Award
2015
·
University of Florida
Study Section Memberships – Advisory Board
2014-2016
·
CIHR Institute Advisory Board of Infection and Immunity
Study Section Memberships – Advisory Board
2014-2015
·
AICR
Study Section Memberships -Advisory Board
2014-2015
·
American Society for Cancer
Study Section Memberships – Advisory Board
2013-2020
·
NIH NCI Chair ZRG1 DKUS-D: Role of the Microflora in the Etiology of Gastrointestinal Cancer
Study Section Memberships – Advisory Board
2011-2020
·
Ad Hoc NIH Gastrointestinal Mucosal Pathobiology (GMBP)
Study Section Memberships – Advisory Board
2010-2013
·
Canadian Institutes of Health Research, Vanier Canada Graduate Scholarships
Admission Committee
2009-2012
·
UNC Biological and Biomedical Sciences Program
IBD: Associate Editor
2008-2016
·
Cell Biology/Biochemistry/Molecular Biology
Study Section Memberships – Advisory Board
2008-2011
·
CCFA Study section (Fellowship and Career Awards)
Study Section
2007-2020
·
NIH Tumor Microenvironment (TME)
IBD: Section Editor
2007-2008
·
Cell Biology/Biochemistry/Molecular Biology
Editorial Board Member
2005-2010
·
Gastroenterology
Fireman Young Scientist Basic Research Award
2005
·
American Gastroenterological Association
Junior Faculty Development Award
2005
·
UNC
University Research Council Award
2004
·
Mucosal Immunology Society
Study Section Memberships – Advisory Board
2003-2007
·
Canadian Institutes of Health Research, Experimental Medicine
Study Section Memberships – Advisory Board
2002-2020
·
Ad Hoc NIH Special Emphasis Panel NIDDK
Editorial Board Member
2001-2009
·
American Journal of Physiology
Anne Ferguson Award
1999
·
Mucosal Immunology Society
Young investigator travel award
1999
·
Mucosal Immunology
Career Development Award
1998-1999
·
CCFA
CCFA Young IBD Investigator Award
1998
·
“Regulation and modulation of the IkB/NF-kB transcriptional system in intestinal epithelial cells”
University Research Council Award
1998
·
University Research Council Award
CCFA young investigator travel award
1996
·
“Immune/non-immune cell interaction in intestinal inflammation” meeting in Florida
CCFA young investigator travel award
1995
·
“Interactions between genetics and microbiology in inflammatory bowel disease” meeting in South Carolina
Ph.D fellowships
1991-1993
·
Laval University
Ph.D fellowship
1990-1991
·
Hôpital Saint-François d’Assise
Teaching Profile
Courses Taught
2018-2023
GMS6065 Fundamentals of Cancer Biology
2016-2019
GMS6001 Fundamentals of Biomedical Sciences I
2018
GMS7979 Advanced Research
2018
GMS7980 Research for Doctoral Dissertation
2013
VME6934 Topics in Veterinary Medical Sciences
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0002-3733-1001
Publications
2023
Intestinal bacteria and colorectal cancer: etiology and treatment
Gut Microbes.
15(1)
[DOI] 10.1080/19490976.2023.2185028.
[PMID] 36927206.
2023
Microbiota Influences on Hematopoiesis and Blood Cancers: New Horizons?
Blood Cancer Discovery.
OF1-OF9
[DOI] 10.1158/2643-3230.bcd-22-0172.
2023
Non-pathogenic microbiota accelerate age-related CpG Island methylation in colonic mucosa
Epigenetics.
18(1)
[DOI] 10.1080/15592294.2022.2160568.
[PMID] 36572998.
2023
Prevalence of genotoxic bacteria in men undergoing biopsy for prostate cancer.
The Prostate.
83(7):663-669
[DOI] 10.1002/pros.24500.
[PMID] 36842100.
2023
Skin microbiome sampling in the preterm neonate.
Pediatric dermatology.
40(1):129-131
[DOI] 10.1111/pde.15158.
[PMID] 36385397.
2023
Western diet influences on microbiome and carcinogenesis.
Seminars in immunology.
67
[DOI] 10.1016/j.smim.2023.101756.
[PMID] 37018910.
2022
Bacteriophage-mediated manipulations of microbiota in gastrointestinal diseases.
Frontiers in microbiology.
13
[DOI] 10.3389/fmicb.2022.1055427.
[PMID] 36466675.
2022
Effect of Routine Gastric Residual Aspiration on the Preterm Infant Fecal Microbiome.
American journal of perinatology.
[DOI] 10.1055/a-1877-6306.
[PMID] 35709728.
2022
Finding clues in unexpected places: detection of pancreatic cancer through the faecal microbiome
Gut.
71(7):1247-1248
[DOI] 10.1136/gutjnl-2021-326710.
[PMID] 35260443.
2022
Fusobacterium is enriched in oral cancer and promotes induction of programmed death-ligand 1 (PD-L1).
Neoplasia (New York, N.Y.).
31
[DOI] 10.1016/j.neo.2022.100813.
[PMID] 35834946.
2022
Group 3 innate lymphoid cell pyroptosis represents a host defence mechanism against Salmonella infection
Nature Microbiology.
7(7):1087-1099
[DOI] 10.1038/s41564-022-01142-8.
[PMID] 35668113.
2022
Gut Microbiota as a Novel Tool to Dissect the Complex Structures of Black Tea Polymers.
Journal of agricultural and food chemistry.
70(16):5005-5014
[DOI] 10.1021/acs.jafc.2c00995.
[PMID] 35420414.
2022
Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice
Cancer Discovery.
12(8):1873-1885
[DOI] 10.1158/2159-8290.cd-21-1273.
2022
Interaction of bacterial genera associated with therapeutic response to immune checkpoint PD-1 blockade in a United States cohort
Genome Medicine.
14(1)
[DOI] 10.1186/s13073-022-01037-7.
[PMID] 35346337.
2022
Intestinal microbiota modulates pancreatic carcinogenesis through intratumoral natural killer cells
Gut Microbes.
14(1)
[DOI] 10.1080/19490976.2022.2112881.
[PMID] 35980869.
2022
MarZIC: A Marginal Mediation Model for Zero-Inflated Compositional Mediators with Applications to Microbiome Data
Genes.
13(6)
[DOI] 10.3390/genes13061049.
[PMID] 35741811.
2022
NTPDase8 protects mice from intestinal inflammation by limiting P2Y6 receptor activation: identification of a new pathway of inflammation for the potential treatment of IBD
Gut.
71(1):43-54
[DOI] 10.1136/gutjnl-2020-320937.
2022
The microbiome, gastrointestinal cancer, and immunotherapy
Journal of Gastroenterology and Hepatology.
37(2):263-272
[DOI] 10.1111/jgh.15742.
[PMID] 34820895.
2022
Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival
JCI Insight.
7(19)
[DOI] 10.1172/jci.insight.147417.
[PMID] 36048542.
2021
Avenanthramide Metabotype from Whole-Grain Oat Intake is Influenced by Faecalibacterium prausnitzii in Healthy Adults.
The Journal of nutrition.
151(6):1426-1435
[DOI] 10.1093/jn/nxab006.
[PMID] 33694368.
2021
Bacteria break barrier to promote metastasis.
Cancer cell.
39(5):598-600
[DOI] 10.1016/j.ccell.2021.03.009.
[PMID] 33891891.
2021
Bacterial Swarmers Enriched During Intestinal Stress Ameliorate Damage.
Gastroenterology.
161(1):211-224
[DOI] 10.1053/j.gastro.2021.03.017.
[PMID] 33741315.
2021
Black Tea Theaflavin Detoxifies Metabolic Toxins in the Intestinal Tract of Mice.
Molecular nutrition & food research.
65(4)
[DOI] 10.1002/mnfr.202000887.
[PMID] 33381889.
2021
Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis
Science.
374(6564):216-224
[DOI] 10.1126/science.abf8403.
2021
Far reach of Fusobacterium nucleatum in cancer metastasis
Gut.
70(8):1427-1429
[DOI] 10.1136/gutjnl-2020-323496.
2021
Gut Microbiota Dysbiosis Associated with Persistent Fatigue in Hematopoietic Cell Transplantation Survivors.
Transplantation and cellular therapy.
27(6):498.e1-498.e8
[DOI] 10.1016/j.jtct.2021.02.017.
[PMID] 33775619.
2021
IFAA: Robust Association Identification and Inference for Absolute Abundance in Microbiome Analyses.
Journal of the American Statistical Association.
116(536):1595-1608
[DOI] 10.1080/01621459.2020.1860770.
[PMID] 35241863.
2021
Implications of the microbiome in the development and treatment of pancreatic cancer: Thinking outside of the box by looking inside the gut.
Neoplasia (New York, N.Y.).
23(2):246-256
[DOI] 10.1016/j.neo.2020.12.008.
[PMID] 33418277.
2021
Increased ACE2 Levels and Mortality Risk of Patients With COVID-19 on Proton Pump Inhibitor Therapy.
The American journal of gastroenterology.
116(8):1638-1645
[DOI] 10.14309/ajg.0000000000001311.
[PMID] 34047305.
2021
Microbiome-Derived Liquid Biopsy: New Hope for Cancer Screening?
Clinical chemistry.
67(3):463-465
[DOI] 10.1093/clinchem/hvaa240.
[PMID] 33277898.
2021
Microbiota in mesenteric adipose tissue from Crohn’s disease promote colitis in mice.
Microbiome.
9(1)
[DOI] 10.1186/s40168-021-01178-8.
[PMID] 34814945.
2021
Microbiota phylogenic analysis revealed decreased abundance of Faecalibacterium prausnitzii, an anti-inflammatory commensal bacterium, in patients with chronic graft-versus-host disease.
Hematology/oncology and stem cell therapy.
14(3):263-265
[DOI] 10.1016/j.hemonc.2021.03.004.
[PMID] 33785388.
2021
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism
Nature Communications.
12(1)
[DOI] 10.1038/s41467-021-24755-9.
[PMID] 34294718.
2021
Shining a Light on Colibactin Biology
Toxins.
13(5)
[DOI] 10.3390/toxins13050346.
[PMID] 34065799.
2021
The gut microbiome of COVID-19 recovered patients returns to uninfected status in a minority-dominated United States cohort.
Gut microbes.
13(1):1-15
[DOI] 10.1080/19490976.2021.1926840.
[PMID] 34100340.
2020
A mutational signature that can be made by a bacterium arises in human colon cancer.
Nature.
580(7802):194-195
[DOI] 10.1038/d41586-020-00818-7.
[PMID] 32203380.
2020
Amending microbiota by targeting intestinal inflammation with TNF blockade attenuates development of colorectal cancer
Nature Cancer.
1(7):723-734
[DOI] 10.1038/s43018-020-0078-7.
[PMID] 33768208.
2020
Baseline Gut Microbiota Composition Is Associated with Major Infections Early after Hematopoietic Cell Transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
26(11):2001-2010
[DOI] 10.1016/j.bbmt.2020.07.023.
[PMID] 32717434.
2020
Characterization of the bacterial microbiome among free-ranging bottlenose dolphins (Tursiops truncatus).
Heliyon.
6(6)
[DOI] 10.1016/j.heliyon.2020.e03944.
[PMID] 32577542.
2020
Dietary iron variably modulates assembly of the intestinal microbiota in colitis-resistant and colitis-susceptible mice.
Gut microbes.
11(1):32-50
[DOI] 10.1080/19490976.2019.1599794.
[PMID] 31179826.
2020
Gut microbiota maturation during early human life induces enterocyte proliferation via microbial metabolites
BMC Microbiology.
20(1)
[DOI] 10.1186/s12866-020-01892-7.
[PMID] 32652929.
2020
Human Colon Mucosal Biofilms and Murine Host Communicate via Altered mRNA and microRNA Expression during Cancer.
mSystems.
5(1)
[DOI] 10.1128/mSystems.00451-19.
[PMID] 31937674.
2020
Microbiota in pancreatic health and disease: the next frontier in microbiome research.
Nature reviews. Gastroenterology & hepatology.
17(1):53-64
[DOI] 10.1038/s41575-019-0242-7.
[PMID] 31811279.
2020
Oral therapy with colonization factor antigen I prevents development of type 1 diabetes in Non-obese Diabetic mice.
Scientific reports.
10(1)
[DOI] 10.1038/s41598-020-62881-4.
[PMID] 32273533.
2020
Seaweed natural products modify the host inflammatory response via Nrf2 signaling and alter colon microbiota composition and gene expression.
Free radical biology & medicine.
146:306-323
[DOI] 10.1016/j.freeradbiomed.2019.09.013.
[PMID] 31536771.
2020
The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View.
Trends in cancer.
6(3):192-204
[DOI] 10.1016/j.trecan.2020.01.004.
[PMID] 32101723.
2019
Campylobacter jejuni promotes colorectal tumorigenesis through the action of cytolethal distending toxin.
Gut.
68(2):289-300
[DOI] 10.1136/gutjnl-2018-317200.
[PMID] 30377189.
2019
Fecal Microbial Transplantation for Diseases Beyond Recurrent Clostridium Difficile Infection
Gastroenterology.
157(3):624-636
[DOI] 10.1053/j.gastro.2019.04.053.
[PMID] 31220424.
2019
Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic.
The Journal of clinical investigation.
129(4):1699-1712
[DOI] 10.1172/JCI124196.
[PMID] 30855275.
2019
Initial microbial community of the neonatal stomach immediately after birth.
Gut microbes.
10(3):289-297
[DOI] 10.1080/19490976.2018.1520578.
[PMID] 30404568.
2019
International Cancer Microbiome Consortium consensus statement on the role of the human microbiome in carcinogenesis.
Gut.
68(9):1624-1632
[DOI] 10.1136/gutjnl-2019-318556.
[PMID] 31092590.
2019
Microbial Colonization Coordinates the Pathogenesis of a Klebsiella pneumoniae Infant Isolate.
Scientific reports.
9(1)
[DOI] 10.1038/s41598-019-39887-8.
[PMID] 30833613.
2019
Microbiota and cancer immunotherapy: in search of microbial signals.
Gut.
68(3):385-388
[DOI] 10.1136/gutjnl-2018-317220.
[PMID] 30530851.
2019
Microbiota facilitates the formation of the aminated metabolite of green tea polyphenol (-)-epigallocatechin-3-gallate which trap deleterious reactive endogenous metabolites.
Free radical biology & medicine.
131:332-344
[DOI] 10.1016/j.freeradbiomed.2018.12.023.
[PMID] 30578921.
2019
Yersiniabactin-Producing Adherent/Invasive Escherichia coli Promotes Inflammation-Associated Fibrosis in Gnotobiotic Il10-/- Mice.
Infection and immunity.
87(11)
[DOI] 10.1128/IAI.00587-19.
[PMID] 31481410.
2018
Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma.
Nature communications.
9(1)
[DOI] 10.1038/s41467-018-04111-0.
[PMID] 29700302.
2018
Colorectal cancer: Hand-in-hand – colorectal cancer metastasizes with microorganisms.
Nature reviews. Gastroenterology & hepatology.
15(3):133-134
[DOI] 10.1038/nrgastro.2017.186.
[PMID] 29339812.
2018
Dual-route targeted vaccine protects efficiently against botulinum neurotoxin A complex.
Vaccine.
36(1):155-164
[DOI] 10.1016/j.vaccine.2017.11.008.
[PMID] 29180028.
2018
Intestinal microbiota enhances pancreatic carcinogenesis in preclinical models.
Carcinogenesis.
39(8):1068-1078
[DOI] 10.1093/carcin/bgy073.
[PMID] 29846515.
2018
Microbial dysbiosis associated with impaired intestinal Na+/H+ exchange accelerates and exacerbates colitis in ex germ free mice
Mucosal Immunology.
2018
Microbial dysbiosis associated with impaired intestinal Na+/H+ exchange accelerates and exacerbates colitis in ex-germ free mice.
Mucosal immunology.
11(5):1329-1341
[DOI] 10.1038/s41385-018-0035-2.
[PMID] 29875400.
2018
Microbial networking in cancer: when two toxins collide.
British journal of cancer.
118(11):1407-1409
[DOI] 10.1038/s41416-018-0101-2.
[PMID] 29773837.
2018
Microbiota-Derived Metabolic Factors Reduce Campylobacteriosis in Mice
Gastroenterology.
154(6):1751-1763.e2
[DOI] 10.1053/j.gastro.2018.01.042.
[PMID] 29408609.
2018
Precision medicine using microbiota.
Science (New York, N.Y.).
359(6371):32-34
[DOI] 10.1126/science.aar2946.
[PMID] 29302001.
2018
Publisher Correction: Bcl11b is essential for licensing Th2 differentiation during helminth infection and allergic asthma.
Nature communications.
9(1)
[DOI] 10.1038/s41467-018-05360-9.
[PMID] 30026604.
2018
Transcription factor Bcl11b is central for Th2 cell differentiation in asthma and immune response to helminths
Nature Communications.
9(1)
2017
Cancer treatment: Bacterial snack attack deactivates a drug.
Nature.
550(7676):337-339
[DOI] 10.1038/550337a.
[PMID] 29052621.
2017
Carcinogenesis and therapeutics: the microbiota perspective.
Nature microbiology.
2
[DOI] 10.1038/nmicrobiol.2017.8.
[PMID] 28225000.
2017
ClbM is a versatile, cation-promiscuous MATE transporter found in the colibactin biosynthetic gene cluster.
Biochemical and biophysical research communications.
482(4):1233-1239
[DOI] 10.1016/j.bbrc.2016.12.018.
[PMID] 27939886.
2017
Human Intestinal Microbiota and Colorectal Cancer: Moving Beyond Associative Studies.
Gastroenterology.
153(6):1475-1478
[DOI] 10.1053/j.gastro.2017.10.030.
[PMID] 29100848.
2017
Locoregional Effects of Microbiota in a Preclinical Model of Colon Carcinogenesis.
Cancer research.
77(10):2620-2632
[DOI] 10.1158/0008-5472.CAN-16-3472.
[PMID] 28416491.
2017
Microbiota as a mediator of cancer progression and therapy.
Translational research : the journal of laboratory and clinical medicine.
179:139-154
[DOI] 10.1016/j.trsl.2016.07.021.
[PMID] 27554797.
2017
Novel insights into microbiome in colitis and colorectal cancer.
Current opinion in gastroenterology.
33(6):422-427
[DOI] 10.1097/MOG.0000000000000399.
[PMID] 28877044.
2017
Optimized multiplex immunofluorescence single-cell analysis reveals tuft cell heterogeneity.
JCI insight.
2(11)
[DOI] 10.1172/jci.insight.93487.
[PMID] 28570279.
2017
The Aryl Hydrocarbon Receptor Preferentially Marks and Promotes Gut Regulatory T Cells.
Cell reports.
21(8):2277-2290
[DOI] 10.1016/j.celrep.2017.10.114.
[PMID] 29166616.
2017
Workshop Report: Modulation of Antitumor Immune Responses by Dietary and Microbial Metabolites.
Journal of the National Cancer Institute.
109(6)
[DOI] 10.1093/jnci/djx040.
[PMID] 30053241.
2016
A Rapid Screenable Assay for Compounds That Protect Against Intestinal Injury in Zebrafish Larva.
Methods in molecular biology (Clifton, N.J.).
1422:281-93
[DOI] 10.1007/978-1-4939-3603-8_25.
[PMID] 27246041.
2016
Altered intestinal microbiota-host mitochondria crosstalk in new onset Crohn’s disease.
Nature communications.
7
[DOI] 10.1038/ncomms13419.
[PMID] 27876802.
2016
Gut Microbiota and a Selectively Bred Taste Phenotype: A Novel Model of Microbiome-Behavior Relationships.
Psychosomatic medicine.
78(5):610-9
[DOI] 10.1097/PSY.0000000000000318.
[PMID] 27035357.
2016
High Purity Galacto-Oligosaccharides Enhance Specific Bifidobacterium Species And Their Metabolic Activity In The Mouse Gut Microbiome.
Beneficial Microbes.
7(2):247-64
[DOI] 10.3920/BM2015.0114.
[PMID] 26839072.
2016
Intestinal Microbiota in Inflammatory Bowel Disease and Carcinogenesis: Implication for Therapeutics.
Clinical pharmacology and therapeutics.
99(6):585-7
[DOI] 10.1002/cpt.348.
[PMID] 26850686.
2016
MATE transport of the E. coli-derived genotoxin colibactin.
Nature microbiology.
1
[DOI] 10.1038/nmicrobiol.2015.9.
[PMID] 27571755.
2016
Microbiota and host immune responses: a love-hate relationship.
Immunology.
147(1):1-10
[DOI] 10.1111/imm.12538.
[PMID] 26439191.
2016
Murine Model of Intestinal Ischemia-reperfusion Injury.
Journal of visualized experiments : JoVE.
(111)
[DOI] 10.3791/53881.
[PMID] 27213580.
2016
The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals.
Cell reports.
14(11):2562-75
[DOI] 10.1016/j.celrep.2016.02.064.
[PMID] 26971998.
2015
Differential Relevance of NF-κB and JNK in the Pathophysiology of Hemorrhage/Resususcitation-Induced Liver Injury after Chronic Ethanol Feeding.
PloS one.
10(9)
[DOI] 10.1371/journal.pone.0137875.
[PMID] 26367181.
2015
Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt.
Nature medicine.
21(8):906-13
[DOI] 10.1038/nm.3908.
[PMID] 26107252.
2015
Microbial activities and intestinal homeostasis: A delicate balance between health and disease.
Cellular and molecular gastroenterology and hepatology.
1(1):28-40
[PMID] 25729763.
2015
Partial Depletion of the Proinflammatory Monocyte Population Is Neuroprotective in the Myenteric Plexus But Not in the Basal Ganglia in a Mptp Mouse Model of Parkinson’s Disease
Brain Behavior and Immunity.
46:154-167
[DOI] 10.1016/j.bbi.2015.01.009.
[PMID] 25637482.
2015
Professor Arlette Darfeuille-Michaud: the discovery of adherent-invasive Escherichia coli.
Journal of Crohn's & colitis.
9(5):373-5
[DOI] 10.1093/ecco-jcc/jjv044.
[PMID] 25759068.
2015
SCFAs Take a Toll En Route to Metabolic Syndrome.
Cell metabolism.
22(6):954-6
[DOI] 10.1016/j.cmet.2015.11.006.
[PMID] 26636491.
2015
The Microbiome and Cancer: Is the ‘Oncobiome’ Mirage Real?
Trends in cancer.
1(1):24-35
[PMID] 26568984.
2015
The Role of Curcumin in Modulating Colonic Microbiota During Colitis and Colon Cancer Prevention.
Inflammatory bowel diseases.
21(11):2483-94
[DOI] 10.1097/MIB.0000000000000522.
[PMID] 26218141.
2014
Bugs and food: a recipe for cancer?
Cell metabolism.
20(6):937-8
[DOI] 10.1016/j.cmet.2014.11.010.
[PMID] 25470545.
2014
Chemotherapy, immunity and microbiota–a new triumvirate?
Nature medicine.
20(2):126-7
[DOI] 10.1038/nm.3473.
[PMID] 24504404.
2014
Chronic Ethanol Feeding Modulates Inflammatory Mediators, Activation Of Nuclear Factor-Κb, And Responsiveness To Endotoxin In Murine Kupffer Cells And Circulating Leukocytes.
Mediators of Inflammation.
2014
[DOI] 10.1155/2014/808695.
[PMID] 24623963.
2014
Commensal microbiota stimulate systemic neutrophil migration through induction of serum amyloid A.
Cellular microbiology.
16(7):1053-67
[DOI] 10.1111/cmi.12257.
[PMID] 24373309.
2014
Could a swimming creature inform us on intestinal diseases? Lessons from zebrafish.
Inflammatory bowel diseases.
20(5):956-66
[DOI] 10.1097/01.MIB.0000442923.85569.68.
[PMID] 24577115.
2014
Do bugs define cancer geography?
The Journal of experimental medicine.
211(3)
[DOI] 10.1084/jem.2113insight3.
[PMID] 24616475.
2014
From promotion to management: the wide impact of bacteria on cancer and its treatment.
BioEssays : news and reviews in molecular, cellular and developmental biology.
36(7):658-64
[DOI] 10.1002/bies.201400015.
[PMID] 24752750.
2014
Fusobacterium and Enterobacteriaceae: important players for CRC?
Immunology letters.
162(2 Pt A):54-61
[DOI] 10.1016/j.imlet.2014.05.014.
[PMID] 24972311.
2014
Glass Microparticulate Ingestion: An Unusual And Difficult-To-Diagnose Cause Of Chronic Abdominal Pain.
Acg Case Reports Journal.
1(3):137-9
[DOI] 10.14309/crj.2014.29.
[PMID] 26157853.
2014
GPR109a: the missing link between microbiome and good health?
Immunity.
40(1):8-10
[DOI] 10.1016/j.immuni.2013.12.009.
[PMID] 24439263.
2014
Gut commensal bacteria and regional Wnt gene expression in the proximal versus distal colon.
The American journal of pathology.
184(3):592-9
[DOI] 10.1016/j.ajpath.2013.11.029.
[PMID] 24418259.
2014
Lactobacillus Acidophilus Ncfm Affects Colonic Mucosal Opioid Receptor Expression In Patients With Functional Abdominal Pain – A Randomised Clinical Study.
Alimentary Pharmacology & Therapeutics.
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Supplementary Table from Human Colon Cancer–Derived <i>Clostridioides difficile</i> Strains Drive Colonic Tumorigenesis in Mice
.
[DOI] 10.1158/2159-8290.22541267.
Supplementary Table from Human Colon Cancer–Derived <i>Clostridioides difficile</i> Strains Drive Colonic Tumorigenesis in Mice
.
[DOI] 10.1158/2159-8290.22541273.v1.
Supplementary Table from Human Colon Cancer–Derived <i>Clostridioides difficile</i> Strains Drive Colonic Tumorigenesis in Mice
.
[DOI] 10.1158/2159-8290.22541264.
Supplementary Table from Human Colon Cancer–Derived <i>Clostridioides difficile</i> Strains Drive Colonic Tumorigenesis in Mice
.
[DOI] 10.1158/2159-8290.22541267.v1.
Supplementary Table from Human Colon Cancer–Derived <i>Clostridioides difficile</i> Strains Drive Colonic Tumorigenesis in Mice
.
[DOI] 10.1158/2159-8290.22541264.v1.
Supplementary Table from Human Colon Cancer–Derived <i>Clostridioides difficile</i> Strains Drive Colonic Tumorigenesis in Mice
.
[DOI] 10.1158/2159-8290.22541273.
Supplementary Table from Human Colon Cancer–Derived <i>Clostridioides difficile</i> Strains Drive Colonic Tumorigenesis in Mice
.
[DOI] 10.1158/2159-8290.22541270.
Supplementary Table from Human Colon Cancer–Derived <i>Clostridioides difficile</i> Strains Drive Colonic Tumorigenesis in Mice
.
[DOI] 10.1158/2159-8290.22541270.v1.
Grants
Feb 2023
ACTIVE
Deciphering microbial contribution to androgen bioavailability in castration resistant prostate cancer patients
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Jul 2022
ACTIVE
Microbiota-mediated enhancement of the anti-tumor effect of natural killer cells
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
May 2022
ACTIVE
Bacteriophage-mediated microbiota modification to prevent colorectal cancer development
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Dec 2021
ACTIVE
Bacteriophages as Modulators of Bacterial Colonization
Role: Other
Funding: NATL INST OF HLTH NIAID
Aug 2021
ACTIVE
Role of RORgt+ (note: g: is gamma symbol) lymphocytes in Gut Tissue Homeostasis
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAID
Jul 2021
ACTIVE
Exploiting microbiota metabolism for colorectal cancer prevention
Role: Principal Investigator
Funding: YALE UNIV
via US ARMY MED RES ACQUISITION
Jun 2021
ACTIVE
Modulation of microbiome function by host-derived noncoding small RNA
Role: Principal Investigator
Funding: NATL INST OF HLTH NIAID
Mar 2019
ACTIVE
Role of the microbiota in DNA methylation and CRC development
Role: Principal Investigator
Funding: CORIELL INSTITUTE FOR MEDICAL RESEARCH
via NATL INST OF HLTH NCI
Jan 2019
ACTIVE
Human milk metabolomics and microbe-host interactions associated with pediatric obesity
Role: Other
Funding: NATL INST OF HLTH NIDDK
Jul 2018
ACTIVE
Role of Bacteria in Colitis-Associated Colon Cancer
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Jan 2018
ACTIVE
The role of the microbiome on pancreatic carcinogenesis in a murine model
Role: Other
Funding: AMER CANCER SOC
Dec 2017
– Feb 2019
Role of the microbiota in DNA methylation and CRC development
Role: Principal Investigator
Funding: TEMPLE UNIVERSITY
via NATL INST OF HLTH NCI
Dec 2017
– Feb 2023
Chemical approaches toward the identification, functional analysis, and biosynthesis of small molecule cyclomodulin
Role: Principal Investigator
Funding: YALE UNIV
via NATL INST OF HLTH NCI
Oct 2016
– Sep 2018
Role of Gram negative bacterial lipopolysaccharide in CXCR4-mediated pancreatic carcinogenesis
Role: Faculty
Funding: ASSOC OF VA SURGEONS FOU
Aug 2016
– Dec 2021
ACE2, Brain, Gut Dysbiosis in Pulmonary Hypertension
Role: Co-Investigator
Funding: NATL INST OF HLTH NHLBI
Jul 2016
– Jun 2019
Impact of host signaling on microbial activities in the development of colitis-associated colorectal cancer
Role: Other
Funding: CROHNS & COLITIS FOUNDATION
Apr 2016
– Sep 2021
Brain-Gut Microbiome-Immune Axis in Hypertension
Role: Project Manager
Funding: NATL INST OF HLTH NHLBI
Dec 2015
– Nov 2019
Mechanism by which H2S-producing bacteria influence development of colorectal cancer
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Jul 2015
ACTIVE
Florida Academic Cancer Center Alliance Seed Grants
Role: Project Manager
Funding: UF HEALTH SHANDS HOSPITAL
Jun 2015
– Nov 2017
Microbial Factors Implicated in the Development of Colorectal Cancer
Role: Principal Investigator
Funding: UF DSR OPPORTUNITY FUND
Feb 2015
ACTIVE
UF Health Cancer Center Pilot Project Grants funded through the Florida Consortium of National Cancer Institute Centers Program
Role: Project Manager
Funding: UF HEALTH SHANDS HOSPITAL
Jan 2015
– Dec 2021
Impact of microbiota-mediated biotransformation of black tea polyphenols on GI health
Role: Principal Investigator
Funding: NATL CTR FOR COMPLEM AND INTEGRATIVE HLT
May 2014
– May 2019
Multiple Sponsors
Role: Principal Investigator
Funding: MULTIPLE SPONSORS
Jul 2013
– Jun 2021
Florida Center for Brain Tumor Research – Statewide Brain Tumor Registry Program at the McKnight Brain Institute
Role: Project Manager
Funding: FL DEPT OF HLTH
Jul 2013
– Mar 2018
Role of Bacteria in Colitis-Associated Colon Cancer
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Jul 2013
– Jun 2016
Regulation of Immunosuppressive Molecules in IBD
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Contact Details
Phones:
- Business:
- (352) 294-5148
Emails:
- Business:
- cjobin@ufl.edu
Addresses:
- Business Mailing:
-
CGRC-461
CGRC-461
2033 MOWRY RD
GAINESVILLE FL 326100001 - Business Street:
-
2033 MOWRY RD
GAINESVILLE FL 32611