Phillip P Toskes

Phillip P Toskes, M.D.

PROFESSOR

Department: MD-GASTROENTEROLOGY
Business Phone: (352) 273-9400
Business Email: toskes@ufl.edu

Publications

2020
Study of the gastrointestinal bioavailability of a pancreatic extract product (Zenpep) in chronic pancreatitis patients with exocrine pancreatic insufficiency.
Pancreatology : official journal of the International Association of Pancreatology (IAP) … [et al.]. 20(6):1092-1102 [DOI] 10.1016/j.pan.2020.07.007. [PMID] 32800653.
2015
Predisposing Factors for Positive D-Xylose Breath Test for Evaluation of Small Intestinal Bacterial Overgrowth: a Retrospective Study of 932 Patients
World Journal of Gastroenterology. 21(15):4574-4582 [DOI] 10.3748/wjg.v21.i15.4574. [PMID] 25914466.
2014
American Pancreatic Association Practice Guidelines in Chronic Pancreatitis: evidence-based report on diagnostic guidelines.
Pancreas. 43(8):1143-62 [DOI] 10.1097/MPA.0000000000000237. [PMID] 25333398.
2013
A pilot retrospective study of the relationship between estrogen use and pancreatitis/pancreatic function in women with chronic abdominal pain.
JOP : Journal of the pancreas. 14(3):237-42 [DOI] 10.6092/1590-8577/1190. [PMID] 23669471.
2012
Correlation of ePFT and EUS to histology: were these really minimal change chronic pancreatitis patients?
The American journal of gastroenterology. 107(3):484; author reply 484-5 [DOI] 10.1038/ajg.2011.460. [PMID] 22388026.
2012
Effect of azithromycin on small bowel motility in patients with gastrointestinal dysmotility.
Scandinavian journal of gastroenterology. 47(4):422-7 [DOI] 10.3109/00365521.2012.654402. [PMID] 22364597.
2012
The significance of the volume of pancreatic juice measured at secretin stimulation testing: a single-center evaluation of 224 classical secretin stimulation tests.
Pancreas. 41(7):1073-9 [DOI] 10.1097/MPA.0b013e318249a271. [PMID] 22481285.
2011
A new 13C breath test to detect vitamin B12 deficiency: a prevalent and poorly diagnosed health problem.
Journal of breath research. 5(4) [DOI] 10.1088/1752-7155/5/4/046001. [PMID] 21697586.
2011
Efficacy of a novel pancreatic enzyme product, EUR-1008 (Zenpep), in patients with exocrine pancreatic insufficiency due to chronic pancreatitis.
Pancreas. 40(3):376-82 [DOI] 10.1097/MPA.0b013e31820b971c. [PMID] 21343835.
2011
Estrogens May Increase the Probability of Pancreatitis and Reduce Pancreatic Function in Women With Chronic Abdominal Pain, Possibly Independent of Triglycerides
Pancreas. 40
2010
A Randomized, Double-Blind, Dose-Response Control, Crossover Study of 2 Doses of Eur-1008 (Zenpep) in Chronic Pancreatitis (Cp) Patients With Exocrine Pancreatic Insufficiency (Epi)
Pancreas. 39
2010
Advantages of azithromycin over erythromycin in improving the gastric emptying half-time in adult patients with gastroparesis.
Journal of neurogastroenterology and motility. 16(4):407-13 [DOI] 10.5056/jnm.2010.16.4.407. [PMID] 21103422.
2010
Comparison of the effect of azithromycin versus erythromycin on antroduodenal pressure profiles of patients with chronic functional gastrointestinal pain and gastroparesis.
Digestive diseases and sciences. 55(3):675-83 [DOI] 10.1007/s10620-009-1038-3. [PMID] 19924535.
2010
Pancrelipase for pancreatic disorders: An update.
Drugs of today (Barcelona, Spain : 1998). 46(11):855-66 [DOI] 10.1358/dot.2010.46.11.1541553. [PMID] 21225024.
2010
Screening and therapy for malnutrition and related gastro-intestinal disorders in systemic sclerosis: recommendations of a North American expert panel.
Clinical and experimental rheumatology. 28(2 Suppl 58):S42-6 [PMID] 20576213.
2010
The First Dose Response Analysis for Azithromycin To Promote Gastric Emptying Using 13C Octanoic Acid Breath Testing
American Journal of Gastroenterology. 105
2010
The management of acute and chronic pancreatitis.
Gastroenterology & hepatology. 6(2 Suppl 3):1-16 [PMID] 20567557.
2009
A pilot study of Octreotide LAR vs. octreotide tid for pain and quality of life in chronic pancreatitis.
JOP : Journal of the pancreas. 10(5):518-22 [PMID] 19734628.
2009
Delivery of Enzymes Into the Duodenum of Subjects With Severe Pancreatic Exocrine Insufficiency (Epi) From a Non Enteric Coated Enzyme Preparation Administered With Omeprazole
Pancreas. 38
2009
Yes, simultaneous damage to both the pancreas and liver are associated in subjects who drink excessive amounts of alcohol!
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 7(11) [DOI] 10.1016/j.cgh.2009.09.001. [PMID] 19744578.
2008
A Randomized, Controlled Study of the Safety and Efficacy of High Versus Low Dose Eur-1008 in Patients With Exocrine Pancreatic Insufficiency (Epi) Associated With Chronic Pancreatitis
American Journal of Gastroenterology. 103
2006
The effects of oral pancreatic enzymes (Creon 10 capsule) on steatorrhea: a multicenter, placebo-controlled, parallel group trial in subjects with chronic pancreatitis.
Pancreas. 33(2):156-62 [PMID] 16868481.
2005
Comparative analysis of direct pancreatic function testing versus morphological assessment by endoscopic ultrasonography for the evaluation of chronic unexplained abdominal pain of presumed pancreatic origin.
Pancreas. 31(1):63-8 [PMID] 15968249.
2005
Diagnosis and management of chronic pancreatitis.
Postgraduate medical journal. 81(958):491-7 [PMID] 16085738.
2005
Evaluation of the Ez-HBT Helicobacter blood test to establish Helicobacter pylori eradication.
Alimentary pharmacology & therapeutics. 22(9):875-80 [PMID] 16225498.
2005
Is the prevalence of small bowel bacterial overgrowth in patients with irritable bowel syndrome increased? The question remains unanswered.
Digestive diseases and sciences. 50(8) [PMID] 16110835.
2005
Prospective evaluation of the accuracy of the intraductal secretin stimulation test in the diagnosis of chronic pancreatitis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 3(7):695-9 [PMID] 16206503.
2004
Chronic pancreatitis: controversies in etiology, diagnosis and treatment.
Revista espanola de enfermedades digestivas. 96(9):649-54; 654 [PMID] 15506908.
2004
Is a 15-minute collection of duodenal secretions after secretin stimulation sufficient to diagnose chronic pancreatitis?
Pancreas. 28(1):89-92 [PMID] 14707736.
2004
Small Bowel Bacterial Overgrowth: Presentation, Diagnosis, and Treatment.
Current treatment options in gastroenterology. 7(1):19-28 [PMID] 14723835.
2003
A new synthetic porcine secretin for facilitation of cannulation of the dorsal pancreatic duct at ERCP in patients with pancreas divisum: a multicenter, randomized, double-blind comparative study.
Gastrointestinal endoscopy. 57(6):643-7 [PMID] 12709690.
2003
Comparison of biologic porcine secretin, synthetic porcine secretin, and synthetic human secretin in pancreatic function testing.
Pancreas. 27(3):230-4 [PMID] 14508127.
2003
Medical therapy for chronic pancreatitis pain.
Current gastroenterology reports. 5(2):110-6 [PMID] 12631450.
2003
Prevalence of gastroparesis in patients with small duct chronic pancreatitis.
Pancreas. 26(3):235-8 [PMID] 12657948.
2003
Small bowel bacterial overgrowth: presentation, diagnosis, and treatment.
Current gastroenterology reports. 5(5):365-72 [PMID] 12959716.
2002
Chronic pancreatitis.
Current opinion in gastroenterology. 18(5):558-62 [PMID] 17033333.
2001
Feedback control of pancreatic exocrine secretion: its relationship to the management of the abdominal pain associated with chronic pancreatitis.
Transactions of the American Clinical and Climatological Association. 112:61-7 [PMID] 11413783.
2000
Synthetic porcine secretin is highly accurate in pancreatic function testing in individuals with chronic pancreatitis.
Pancreas. 21(3):262-5 [PMID] 11039470.
1999
Comparison of [13C]urea blood test to [13C]urea breath test for the diagnosis of Helicobacter pylori.
The American journal of gastroenterology. 94(4):959-61 [PMID] 10201464.
1999
The 13C-urea blood test accurately detects active Helicobacter pylori infection: a United States, multicenter trial.
The American journal of gastroenterology. 94(6):1522-4 [PMID] 10364018.
1999
The changing nature of small intestine bacterial overgrowth.
Current gastroenterology reports. 1(4):267-8 [PMID] 10980960.
1999
Update on diagnosis and management of chronic pancreatitis.
Current gastroenterology reports. 1(2):145-53 [PMID] 10980942.
1998
Can a meta-analysis that mixes apples with oranges be used to demonstrate that pancreatic enzymes do not decrease abdominal pain in patients with chronic pancreatitis?
The American journal of gastroenterology. 93(8):1396-8 [PMID] 9707092.
1997
Acid steatocrit: a simple, rapid gravimetric method to determine steatorrhea.
The American journal of gastroenterology. 92(12):2280-4 [PMID] 9399770.
1997
Faecal elastase 1.
Gut. 41(3) [PMID] 18668947.
1997
Faecal elastase 1.
Gut. 41(3) [PMID] 9378408.
1996
Fecal pancreatic elastase 1 is inaccurate in the diagnosis of chronic pancreatitis.
Pancreas. 13(3):226-30 [PMID] 8884841.
1996
Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene.
Nature genetics. 14(2):141-5 [PMID] 8841182.
1995
Acute pancreatitis. Medical management.
Critical care clinics. 11(2):295-309 [PMID] 7788533.
1995
Medical management of chronic pancreatitis.
Scandinavian journal of gastroenterology. Supplement. 208:74-80 [PMID] 7777809.
1995
What does an abnormal pancreatogram mean?
Gastrointestinal endoscopy clinics of North America. 5(1):105-23 [PMID] 7728340.
1994
Digestive Health Initiative launches with the Helicobacter pylori Education Program.
The American journal of gastroenterology. 89(11) [PMID] 7942753.
1994
Is there a relationship between hypertriglyceridemia and development of alcohol- or gallstone-induced pancreatitis?
Gastroenterology. 106(3):810-2 [PMID] 8119553.
1993
Bacterial overgrowth of the gastrointestinal tract.
Advances in internal medicine. 38:387-407 [PMID] 8438647.
1993
Calcium polycarbophil compared with placebo in irritable bowel syndrome.
Alimentary pharmacology & therapeutics. 7(1):87-92 [PMID] 8439642.
1991
Controversies, dilemmas, and dialogues. Is there an effective nonsurgical treatment for pain in chronic pancreatitis?
The American journal of gastroenterology. 86(1):26-9 [PMID] 1986549.
1991
Hope for the treatment of intestinal scleroderma.
The New England journal of medicine. 325(21):1508-9 [PMID] 1944429.
1990
Hyperlipidemic pancreatitis.
Gastroenterology clinics of North America. 19(4):783-91 [PMID] 2269517.
1989
Systemic lupus erythematosus presenting initially with acute pancreatitis and a review of the literature.
The American journal of the medical sciences. 297(1):38-41 [PMID] 2643879.
1987
Bentiromide test is not affected in patients with small bowel disease or liver disease.
Pancreas. 2(1):44-7 [PMID] 3494995.
1986
Comparison of the 1-gram [14C]xylose, 10-gram lactulose-H2, and 80-gram glucose-H2 breath tests in patients with small intestine bacterial overgrowth.
Gastroenterology. 91(6):1447-51 [PMID] 3770368.
1986
Congenital pancreatic hypoplasia: a syndrome of exocrine and endocrine pancreatic insufficiency.
The Journal of pediatrics. 109(3):465-8 [PMID] 3746536.
1986
Negative feedback inhibition of pancreatic exocrine secretion in humans.
Advances in experimental medicine and biology. 199:143-52 [PMID] 3799274.
1985
Diagnosis of chronic pancreatitis and exocrine insufficiency.
Hospital practice (Office ed.). 20(10):97-100, 102 [PMID] 3930547.
1985
Elevated fasting cholecystokinin levels in pancreatic exocrine impairment: evidence to support feedback regulation.
The Journal of laboratory and clinical medicine. 105(3):282-5 [PMID] 3973464.
1985
Recurrent acute pancreatitis.
Hospital practice (Office ed.). 20(7):85-92 [PMID] 3924943.
1984
Breath tests in the diagnosis of small intestine bacterial overgrowth.
Critical reviews in clinical laboratory sciences. 21(3):269-81 [PMID] 6439469.
1984
Protease-specific suppression of pancreatic exocrine secretion.
Gastroenterology. 87(1):44-52 [PMID] 6202586.
1984
The bentiromide test for pancreatic exocrine insufficiency.
Pharmacotherapy. 4(2):74-80 [PMID] 6371722.
1984
Trypsin-like immunoreactivity as a test for pancreatic insufficiency.
The New England journal of medicine. 310(20):1307-9 [PMID] 6717495.
1983
Acute and chronic pancreatitis.
Disease-a-month : DM. 29(6):1-81 [PMID] 6549974.
1983
Bentiromide as a test of exocrine pancreatic function in adult patients with pancreatic exocrine insufficiency. Determination of appropriate dose and urinary collection interval.
Gastroenterology. 85(3):565-9 [PMID] 6603385.
1983
The use of breath tests in the study of malabsorption.
Clinics in gastroenterology. 12(2):591-610 [PMID] 6409472.
1981
Alteration of CO2 production during nonfasting isotopic CO2 breath tests: concise communication.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 22(11):955-8 [PMID] 6795320.
1981
Importance of anaerobic bacteria in the cobalamin malabsorption of the experimental rat blind loop syndrome.
Gastroenterology. 80(2):313-20 [PMID] 7450422.
1981
Protein-losing enteropathy in the human and experimental rat blind-loop syndrome.
Gastroenterology. 80(3):504-9 [PMID] 7450442.
1980
Comparison of the one-gram d-[14C]xylose breath test to the [14C]bile acid breath test in patients with small-intestine bacterial overgrowth.
Digestive diseases and sciences. 25(1):53-8 [PMID] 7353451.
1980
Current concepts of cobalamin (vitamin B12) absorption and malabsorption.
Journal of clinical gastroenterology. 2(3):287-97 [PMID] 7005313.
1980
Does a negative feedback system for the control of pancreatic exocrine secretion exist and is it of any clinical significance?
The Journal of laboratory and clinical medicine. 95(1):11-2 [PMID] 7350237.
1980
Malabsorption of protein-bound cobalamin but not unbound cobalamin during cimetidine administration.
Digestive diseases and sciences. 25(3):188-91 [PMID] 6768534.
1980
The morphine-prostigmin provocative test–is it useful for making clinical decisions?
Gastroenterology. 78(4):728-31 [PMID] 6153371.
1979
Clinically significant vitamin B12 deficiency secondary to malabsorption of protein-bound vitamin B12.
Digestive diseases and sciences. 24(5):397-402 [PMID] 378625.
1979
Detection of small intestine bacterial overgrowth by means of a 14C-D-xylose breath test.
Gastroenterology. 77(1):75-82 [PMID] 447030.
1979
Non-diabetic retinal abnormalities in chronic pancreatitis.
The New England journal of medicine. 300(17):942-6 [PMID] 431561.
1979
Small intestine bacterial overgrowth.
Gastroenterology. 76(5 Pt 1):1035-55 [PMID] 437407.
1978
Xylose catabolism in the experimental rat blind loop syndrome: studies, including use of a newly developed d-[14C]xylose breath test.
Gastroenterology. 74(4):691-7 [PMID] 631506.
1977
Evidence that pancreatic proteases enhance vitamin B12 absorption by acting on curde preparations of hog gastric intrinsic factor and human gastric juice.
Gastroenterology. 72(1):31-6 [PMID] 318582.
1976
Gastrointestinal bleeding and iron absorption in the experimental blind loop syndrome.
The American journal of clinical nutrition. 29(7):754-7 [PMID] 1084685.
1976
Malabsorption following gastric resection.
Major problems in clinical surgery. 20:129-46 [PMID] 957777.
1975
Small intestinal mucosal injury in the experimental blind loop syndrome. Light- and electron-microscopic and histochemical studies.
Gastroenterology. 68(5 Pt 1):1193-203 [PMID] 1126607.
1973
Malabsorption of crystalline vitamin B 12 in cystic fibrosis.
The New England journal of medicine. 288(18):949-50 [PMID] 4693247.
1973
Specificity of the correction of vitamin B12 malabsorption by pancreatic extract and its clinical significance.
Gastroenterology. 65(2):199-204 [PMID] 4720022.
1973
The value of the gelatin infusion test in the diagnosis of pancreatic exocrine insufficiency in patients with Billroth. II. Anastomoses.
The American journal of digestive diseases. 18(2):147-50 [PMID] 4683455.
1973
Trypsin-like nature of the pancreatic factor that corrects vitamin B12 malabsorption associated with pancreatic dysfunction.
The Journal of clinical investigation. 52(7):1660-4 [PMID] 4718958.
1973
Vitamin B 12 absorption and malabsorption.
Gastroenterology. 65(4):662-83 [PMID] 4593465.
1972
Selective inhibition of vitamin B 12 absorption by para-aminosalicylic acid.
Gastroenterology. 62(6):1232-7 [PMID] 5050320.
1972
The role of the pancreas in vitamin B 12 absorption: studies of vitamin B 12 absorption in partially pancreatectomized rats.
The Journal of clinical investigation. 51(2):216-23 [PMID] 5009110.
1971
Vitamin B 12 malabsorption in chronic pancreatic insufficiency.
The New England journal of medicine. 284(12):627-32 [PMID] 5547614.
1970
Significance of cyclic AMP in the regulation of exocrine pancreas secretion.
Experientia. 26(5):515-7 [PMID] 4315525.

Contact Details

Phones:
Business:
(352) 273-9400
Emails:
Business:
toskes@ufl.edu
Addresses:
Business Mailing:
PO Box 100214
GAINESVILLE FL 32610
Business Street:
HD608
GAINESVILLE FL 326100001