Ye Yang

Ye Yang

Assistant Scientist

Department: MD-GASTROENTEROLOGY
Business Phone: (352) 294-5112
Business Email: ye.yang@medicine.ufl.edu

On This Page

Accomplishments

  1. Research Fellowship Award

    Crohn’s & Colitis Foundation of America

  2. William R. Sistrum Memorial Scholarship

    University of Oregon

  3. Cancer Federation Fellowship

    University of Oregon

  4. Outstanding Student Scholarship

    University of Science & Technology of China

Research Profile

I am interested in understanding what/how host-microbe interactions influence host health and disease development. My Ph.D. study was on the regulation and function of alkaline phosphatase (ALP) genes in gut homeostasis and host responses to enteric pathogens using genetically manipulated zebrafish, mice and bacteria (Edwardsiella tarda).

I joined Dr. Christian Jobin’s lab in 2013 to study how host-microbe interactions impact intestinal pathologies (e.g., IBD, CRC, etc.) and how one can manipulate these interactions for better health. My research focuses on the interplay between host and colibactin-producing E. coli during colitis and tumor development. Using various model organisms (bacterium, zebrafish and mouse) and a range of techniques (molecular cloning, genome editing, sequencing, QPCR, in situ hybridization, immunochemistry, comet assay, microinjection, western blot, etc), I set to define the genetic elements and signaling pathways from both the host and microbe sides that contribute colitis and tumor development.

Publications

Academic Articles

Grants

  1. Interaction between dietary taurine and microbiota sulfur metabolism in the development of colorectal cancer

    Active

    Role:
    Co-Investigator
    Funding:
    NATL INST OF HLTH NCI
  2. UF HEALTH CANCER CENTER PILOT PROJECTS GRANTS FUNDED THROUGHTHE FLORIDA CONSORTIUM OF NATIONAL CANCER INSTITUTE CENTER

    Active

    Role:
    Project Manager
    Funding:
    UF HEALTH SHANDS HOSPITAL
  3. Impact of host signaling on microbial activities in the development of colitis-associated colorectal cancer

    Role:
    Principal Investigator
    Funding:
    CROHNS & COLITIS FOUNDATION

Education

  1. PhD

    University of Oregon

  2. BSc

    University of Science & Technology of China

Contact Details

Phones:
Business:
(352) 294-5112
Emails:
Addresses:
Business Mailing:
2033 MOWRY RD # CGRC451
GAINESVILLE FL 326103010
Business Street:
2033 MOWRY RD # CGRC451
GAINESVILLE FL 326103010