Rui Xiao
Lab Technician

Research Summary


I am interested in understanding the role of DNA methylation, or DNAm, in host-microbe interaction. My Master’s research was done in the Hawaiian bobtail squid model studying the impact of beneficial symbiosis on host epigenome. Specifically, I studied the cross talk between symbiont and host DNA methylome using targeted bisulfite sequencing, immunofluorescence and High Performance Liquid Chromatography. I have also developed analysis pipeline for 3rd Generation sequencing technology, for example Oxford Nanopore and PacBio SMRT, to study the functionality of DNA methylation. I am currently working in Dr. Jobin’s lab as a research technician providing support fro the lab’s varies projects. My current main research project is assisting Dr. Jillian Pope in studying the role of Microbiota in host DNA methylation and colorectal cancer development.